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(2E,16E)-(4S,5R,6S,8R,9S,10S,12S,13S,14R)-5,9,13-Tris-(tert-butyl-dimethyl-silanyloxy)-17-iodo-4,6,8,10,12,14-hexamethyl-7,11-dioxo-heptadeca-2,16-dienoic acid

(2E,16E)-(4S,5R,6S,8R,9S,10S,12S,13S,14R)-5,9,13-Tris-(tert-butyl-dimethyl-silanyloxy)-17-iodo-4,6,8,10,12,14-hexamethyl-7,11-dioxo-heptadeca-2,16-dienoic acid

CAS号：1026682-97-2

英文名：(2E,16E)-(4S,5R,6S,8R,9S,10S,12S,13S,14R)-5,9,13-Tris-(tert-butyl-dimethyl-silanyloxy)-17-iodo-4,6,8,10,12,14-hexamethyl-7,11-dioxo-heptadeca-2,16-dienoic acid

分子式：C41H79IO7Si3

分子量：895.223

合成路线

(3E,5R,6S,7S)-6,8-O-[bis-(1,1-dimethylethyl)silylene]-5,7-dimethylhex-3-enoic acid methyl ester

(3E,5R,6S,7S)-6,8-O-[bis-(1,1-dimethylethyl)silylene]-5,7-dimethylhex-3-enoic acid methyl ester

(2E,16E)-(4S,5R,6S,8R,9S,10S,12S,13S,14R)-5,9,13-Tris-(tert-butyl-dimethyl-silanyloxy)-17-iodo-4,6,8,10,12,14-hexamethyl-7,11-dioxo-heptadeca-2,16-dienoic acid

(2E,16E)-(4S,5R,6S,8R,9S,10S,12S,13S,14R)-5,9,13-Tris-(tert-butyl-dimethyl-silanyloxy)-17-iodo-4,6,8,10,12,14-hexamethyl-7,11-dioxo-heptadeca-2,16-dienoic acid

(5R,6S,7R,8S,9S,10R,11S)-(E)-methyl-12-(tert-butyldimethylsilyloxy)-8-10-O-[bis-(1-methylethyl)silylene]-5,7,9,11-tetramethyl-4-ethyl-3-dodecenoate

(5R,6S,7R,8S,9S,10R,11S)-(E)-methyl-12-(tert-butyldimethylsilyloxy)-8-10-O-[bis-(1-methylethyl)silylene]-5,7,9,11-tetramethyl-4-ethyl-3-dodecenoate

(2E,16E)-(4S,5R,6S,8R,9S,10S,12S,13S,14R)-5,9,13-Tris-(tert-butyl-dimethyl-silanyloxy)-17-iodo-4,6,8,10,12,14-hexamethyl-7,11-dioxo-heptadeca-2,16-dienoic acid

(2E,16E)-(4S,5R,6S,8R,9S,10S,12S,13S,14R)-5,9,13-Tris-(tert-butyl-dimethyl-silanyloxy)-17-iodo-4,6,8,10,12,14-hexamethyl-7,11-dioxo-heptadeca-2,16-dienoic acid

(5R,6S,7S)-(E)-methyl-8-[(tert-butyldiphenylsilyl)oxy]-6-hydroxy-5,7-dimethyl-3-octenoate

(5R,6S,7S)-(E)-methyl-8-[(tert-butyldiphenylsilyl)oxy]-6-hydroxy-5,7-dimethyl-3-octenoate

(2E,16E)-(4S,5R,6S,8R,9S,10S,12S,13S,14R)-5,9,13-Tris-(tert-butyl-dimethyl-silanyloxy)-17-iodo-4,6,8,10,12,14-hexamethyl-7,11-dioxo-heptadeca-2,16-dienoic acid

(2E,16E)-(4S,5R,6S,8R,9S,10S,12S,13S,14R)-5,9,13-Tris-(tert-butyl-dimethyl-silanyloxy)-17-iodo-4,6,8,10,12,14-hexamethyl-7,11-dioxo-heptadeca-2,16-dienoic acid

上游原料

(5R,6S,7S)-(E)-methyl-8-[(tert-butyldiphenylsilyl)oxy]-6-hydroxy-5,7-dimethyl-3-octenoate (3E,5R,6S,7S)-6,8-O-[bis-(1,1-dimethylethyl)silylene]-5,7-dimethylhex-3-enoic acid methyl ester (5R,6S,7R,8S,9S,10R,11S)-(E)-methyl-12-(tert-butyldimethylsilyloxy)-8-10-O-[bis-(1-methylethyl)silylene]-5,7,9,11-tetramethyl-4-ethyl-3-dodecenoate

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