百科

{(S)-1-((1S,2S,4S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-isobutyl-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexylcarbamoyl)-2-[1-(toluene-4-sulfonyl)-1H-imidazol-4-yl]-ethyl}-carbamic acid tert-butyl ester

CAS号：103372-33-4

英文名：{(S)-1-((1S,2S,4S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-isobutyl-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexylcarbamoyl)-2-[1-(toluene-4-sulfonyl)-1H-imidazol-4-yl]-ethyl}-carbamic acid tert-butyl ester

分子式：C48H77N7O8SSi

分子量：940.318

合成路线

103372-32-3

N-<Nα-<4(S)-<(tert-butyldimethylsilyl)oxy>-5(S)-<(tert-butyloxycarbonyl)amino>-2(S)-isopropyl-7-methyloctanoyl>-L-isoleucyl>-2-pyridylmethylamine

103372-33-4

{(S)-1-((1S,2S,4S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-isobutyl-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexylcarbamoyl)-2-[1-(toluene-4-sulfonyl)-1H-imidazol-4-yl]-ethyl}-carbamic acid tert-butyl ester

上游原料

N-<Nα-<4(S)-<(tert-butyldimethylsilyl)oxy>-5(S)-<(tert-butyloxycarbonyl)amino>-2(S)-isopropyl-7-methyloctanoyl>-L-isoleucyl>-2-pyridylmethylamine

下游产品

(2S,4S,5S)-5-{(S)-2-Amino-3-[1-(toluene-4-sulfonyl)-1H-imidazol-4-yl]-propionylamino}-4-hydroxy-2-isopropyl-7-methyl-octanoic acid {(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide tert-butyl (S)-2-((3S,6S,9S,10S,12S,15S)-3-benzyl-15-((S)-sec-butyl)-10-hydroxy-9-isobutyl-12-isopropyl-4,7,13,16-tetraoxo-18-(pyridin-2-yl)-6-((1-tosyl-1H-imidazol-4-yl)methyl)-2-oxa-5,8,14,17-tetraazaoctadecyl)pyrrolidine-1-carboxylate