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(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

CAS号：103384-47-0

英文名：(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

分子式：C28H45ClO9Si

分子量：589.19

合成路线

methyl (5S,6R)-5,6-diacetoxy-7-(tert-butyldiphenylsilyloxy)heptanoate

methyl (5S,6R)-5,6-diacetoxy-7-(tert-butyldiphenylsilyloxy)heptanoate

(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

methyl (5S,6S)-5,6-diacetoxy-7-hydroxyheptanoate

methyl (5S,6S)-5,6-diacetoxy-7-hydroxyheptanoate

(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

methyl (5S,6R)-5,6-diacetoxy-7-hydroxyheptanoate

methyl (5S,6R)-5,6-diacetoxy-7-hydroxyheptanoate

(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

methyl (5S,6R)-5,6-diacetoxy-6-formylheptanoate

methyl (5S,6R)-5,6-diacetoxy-6-formylheptanoate

(R)-2-Chloro-4-((Z)-oct-2-enyl)-4-trimethylsilanyloxy-cyclopent-2-enone

(R)-2-Chloro-4-((Z)-oct-2-enyl)-4-trimethylsilanyloxy-cyclopent-2-enone

(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

methyl (5S,6R)-5,6-diacetoxy-6-formylheptanoate

methyl (5S,6R)-5,6-diacetoxy-6-formylheptanoate

(R)-2-Chloro-4-((Z)-oct-2-enyl)-4-trimethylsilanyloxy-cyclopent-2-enone

(R)-2-Chloro-4-((Z)-oct-2-enyl)-4-trimethylsilanyloxy-cyclopent-2-enone

(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

methyl (5S,6S)-5,6-dihydroxy-7-<(tetrahydropyran-2-yl)oxy>heptanoate

methyl (5S,6S)-5,6-dihydroxy-7-<(tetrahydropyran-2-yl)oxy>heptanoate

(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

methyl (5S,6S)-5,6-diacetoxy-7-<(tetrahydropyran-2-yl)oxy>heptanoate

methyl (5S,6S)-5,6-diacetoxy-7-<(tetrahydropyran-2-yl)oxy>heptanoate

(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

methyl (5S,6R)-5,6-dihydroxy-7-(tert-butyldiphenylsilyloxy)heptanoate

methyl (5S,6R)-5,6-dihydroxy-7-(tert-butyldiphenylsilyloxy)heptanoate

(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

(5S,6S)-5,6-Dihydroxy-7-(tetrahydro-pyran-2-yloxy)-heptanoic acid

(5S,6S)-5,6-Dihydroxy-7-(tetrahydro-pyran-2-yloxy)-heptanoic acid

(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

(4R)-2-chloro-4-(trimethylsiloxy)-4-((Z)-2-octenyl)-5-((2R,3S)-6-carbomethoxy-2,3-diacetoxy-1-hydroxyhexyl)-2-cyclopentenone

上游原料

methyl (5S,6R)-5,6-diacetoxy-6-formylheptanoate methyl (5S,6R)-5,6-diacetoxy-6-formylheptanoate (R)-2-Chloro-4-((Z)-oct-2-enyl)-4-trimethylsilanyloxy-cyclopent-2-enone methyl (5S,6S)-5,6-dihydroxy-7-<(tetrahydropyran-2-yl)oxy>heptanoate methyl (5S,6S)-5,6-diacetoxy-7-<(tetrahydropyran-2-yl)oxy>heptanoate methyl (5S,6R)-5,6-diacetoxy-7-hydroxyheptanoate (5S,6S)-5,6-Dihydroxy-7-(tetrahydro-pyran-2-yloxy)-heptanoic acid methyl (5S,6R)-5,6-dihydroxy-7-(tert-butyldiphenylsilyloxy)heptanoate methyl (5S,6R)-5,6-diacetoxy-7-(tert-butyldiphenylsilyloxy)heptanoate methyl (5S,6S)-5,6-diacetoxy-7-hydroxyheptanoate

下游产品

(5S,6S)-5,6-Diacetoxy-7-[(S)-4-chloro-2-hydroxy-2-((Z)-oct-2-enyl)-5-oxo-cyclopent-3-en-(Z)-ylidene]-heptanoic acid methyl ester (Z)-7,8-punaglandin 4 (5S,6R)-5,6-Diacetoxy-7-[(S)-4-chloro-2-hydroxy-2-((Z)-oct-2-enyl)-5-oxo-cyclopent-3-en-(E)-ylidene]-heptanoic acid methyl ester punaglandin 4