百科

4-((4S,5S)-5-{[(R)-4-Chloro-2-methoxymethoxy-2-((Z)-oct-2-enyl)-5-oxo-cyclopent-3-enyl]-hydroxy-methyl}-2,2-dimethyl-[1,3]dioxolan-4-yl)-butyric acid methyl ester

4-((4S,5S)-5-{[(R)-4-Chloro-2-methoxymethoxy-2-((Z)-oct-2-enyl)-5-oxo-cyclopent-3-enyl]-hydroxy-methyl}-2,2-dimethyl-[1,3]dioxolan-4-yl)-butyric acid methyl ester

CAS号：103477-32-3

英文名：4-((4S,5S)-5-{[(R)-4-Chloro-2-methoxymethoxy-2-((Z)-oct-2-enyl)-5-oxo-cyclopent-3-enyl]-hydroxy-methyl}-2,2-dimethyl-[1,3]dioxolan-4-yl)-butyric acid methyl ester

分子式：C26H41ClO8

分子量：517.052

合成路线

(R)-2-Chloro-4-methoxymethoxy-4-((Z)-oct-2-enyl)-cyclopent-2-enone

(R)-2-Chloro-4-methoxymethoxy-4-((Z)-oct-2-enyl)-cyclopent-2-enone

methyl (5S,6R)-5,6-isopropylidenedioxy-7-oxo-heptanoate

methyl (5S,6R)-5,6-isopropylidenedioxy-7-oxo-heptanoate

4-((4S,5S)-5-{[(R)-4-Chloro-2-methoxymethoxy-2-((Z)-oct-2-enyl)-5-oxo-cyclopent-3-enyl]-hydroxy-methyl}-2,2-dimethyl-[1,3]dioxolan-4-yl)-butyric acid methyl ester

4-((4S,5S)-5-{[(R)-4-Chloro-2-methoxymethoxy-2-((Z)-oct-2-enyl)-5-oxo-cyclopent-3-enyl]-hydroxy-methyl}-2,2-dimethyl-[1,3]dioxolan-4-yl)-butyric acid methyl ester

上游原料

methyl (5S,6R)-5,6-isopropylidenedioxy-7-oxo-heptanoate (R)-2-Chloro-4-methoxymethoxy-4-((Z)-oct-2-enyl)-cyclopent-2-enone

下游产品

(5S,6S)-5,6-Diacetoxy-7-[(S)-4-chloro-2-methoxymethoxy-2-((Z)-oct-2-enyl)-5-oxo-cyclopent-3-en-(E)-ylidene]-heptanoic acid methyl ester (5S,6S)-7-[(S)-4-Chloro-2-methoxymethoxy-2-((Z)-oct-2-enyl)-5-oxo-cyclopent-3-en-(E)-ylidene]-5,6-dihydroxy-heptanoic acid methyl ester 4-{(4S,5S)-5-[(S)-4-Chloro-2-methoxymethoxy-2-((Z)-oct-2-enyl)-5-oxo-cyclopent-3-en-(Z)-ylidenemethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-butyric acid methyl ester 4-{(4S,5S)-5-[(S)-4-Chloro-2-methoxymethoxy-2-((Z)-oct-2-enyl)-5-oxo-cyclopent-3-en-(E)-ylidenemethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-butyric acid methyl ester punaglandin 4