4-(4-methylpiperazin-1-yl)-2-[(tetrahydropyran-4-yl)-(2,2,2-trifluoroacetyl)amino]benzoyl chloride

4-(4-methylpiperazin-1-yl)-2-[(tetrahydropyran-4-yl)-(2,2,2-trifluoroacetyl)amino]benzoyl chloride

CAS号：1034976-52-7

英文名：4-(4-methylpiperazin-1-yl)-2-[(tetrahydropyran-4-yl)-(2,2,2-trifluoroacetyl)amino]benzoyl chloride

分子式：C19H23ClF3N3O3

分子量：433.852

合成路线

tert-butyl 2-amino-4-(4-methylpiperazin-1-yl)benzoate

tert-butyl 2-amino-4-(4-methylpiperazin-1-yl)benzoate

4-(4-methylpiperazin-1-yl)-2-[(tetrahydropyran-4-yl)-(2,2,2-trifluoroacetyl)amino]benzoyl chloride

4-(4-methylpiperazin-1-yl)-2-[(tetrahydropyran-4-yl)-(2,2,2-trifluoroacetyl)amino]benzoyl chloride

tert-butyl 4-(4-methylpiperazin-1-yl)-2-(tetrahydropyran-4-ylamino)benzoate

tert-butyl 4-(4-methylpiperazin-1-yl)-2-(tetrahydropyran-4-ylamino)benzoate

4-(4-methylpiperazin-1-yl)-2-[(tetrahydropyran-4-yl)-(2,2,2-trifluoroacetyl)amino]benzoyl chloride

4-(4-methylpiperazin-1-yl)-2-[(tetrahydropyran-4-yl)-(2,2,2-trifluoroacetyl)amino]benzoyl chloride

tert-butyl 4-(4-methylpiperazin-1-yl)-2-(2,2,2-trifluoro-N-(tetrahydropyran-4-yl)-acetamido)benzoate

tert-butyl 4-(4-methylpiperazin-1-yl)-2-(2,2,2-trifluoro-N-(tetrahydropyran-4-yl)-acetamido)benzoate

4-(4-methylpiperazin-1-yl)-2-[(tetrahydropyran-4-yl)-(2,2,2-trifluoroacetyl)amino]benzoyl chloride

4-(4-methylpiperazin-1-yl)-2-[(tetrahydropyran-4-yl)-(2,2,2-trifluoroacetyl)amino]benzoyl chloride

上游原料

tert-butyl 4-(4-methylpiperazin-1-yl)-2-(tetrahydropyran-4-ylamino)benzoate tert-butyl 2-amino-4-(4-methylpiperazin-1-yl)benzoate tert-butyl 4-(4-methylpiperazin-1-yl)-2-(2,2,2-trifluoro-N-(tetrahydropyran-4-yl)-acetamido)benzoate

下游产品

N-[5-(3,5-difluoro-benzenesulfonyl)-1-trityl-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-[(tetrahydro-pyran-4-yl)-(2,2,2-trifluoro-acetyl)-amino]-benzamide