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(4S,6S,8E,10E,12E)-1-(imidazol-1'-yl)-4,6,12-trimethyl-4-(2-trimethylsilylethoxymethoxy)tetradeca-8,10,12-trien-1-one

(4S,6S,8E,10E,12E)-1-(imidazol-1'-yl)-4,6,12-trimethyl-4-(2-trimethylsilylethoxymethoxy)tetradeca-8,10,12-trien-1-one

CAS号：104701-94-2

英文名：(4S,6S,8E,10E,12E)-1-(imidazol-1'-yl)-4,6,12-trimethyl-4-(2-trimethylsilylethoxymethoxy)tetradeca-8,10,12-trien-1-one

分子式：C26H44N2O3Si

分子量：460.725

合成路线

(2R,4R)-5-(dimethyl-t-butylsiloxy)-2,4-dimethylpentane-1,2-diol

(2R,4R)-5-(dimethyl-t-butylsiloxy)-2,4-dimethylpentane-1,2-diol

(4S,6S,8E,10E,12E)-1-(imidazol-1'-yl)-4,6,12-trimethyl-4-(2-trimethylsilylethoxymethoxy)tetradeca-8,10,12-trien-1-one

(4S,6S,8E,10E,12E)-1-(imidazol-1'-yl)-4,6,12-trimethyl-4-(2-trimethylsilylethoxymethoxy)tetradeca-8,10,12-trien-1-one

(2R,4R)-5-(dimethyl-t-butylsiloxy)-2-hydroxy-2,4-dimethylpentanal

(2R,4R)-5-(dimethyl-t-butylsiloxy)-2-hydroxy-2,4-dimethylpentanal

(4S,6S,8E,10E,12E)-1-(imidazol-1'-yl)-4,6,12-trimethyl-4-(2-trimethylsilylethoxymethoxy)tetradeca-8,10,12-trien-1-one

(4S,6S,8E,10E,12E)-1-(imidazol-1'-yl)-4,6,12-trimethyl-4-(2-trimethylsilylethoxymethoxy)tetradeca-8,10,12-trien-1-one

(4R,6R,2E)-methyl 7-(dimethyl-t-butylsiloxy)-4-hydroxy-4,6-dimethylhept-2-enoate

(4R,6R,2E)-methyl 7-(dimethyl-t-butylsiloxy)-4-hydroxy-4,6-dimethylhept-2-enoate

(4S,6S,8E,10E,12E)-1-(imidazol-1'-yl)-4,6,12-trimethyl-4-(2-trimethylsilylethoxymethoxy)tetradeca-8,10,12-trien-1-one

(4S,6S,8E,10E,12E)-1-(imidazol-1'-yl)-4,6,12-trimethyl-4-(2-trimethylsilylethoxymethoxy)tetradeca-8,10,12-trien-1-one

(4R,6R,2E)-methyl 7-hydroxy-4,6-dimethyl-4-(2-trimethylsilylethoxymethoxy)hept-2-enoate

(4R,6R,2E)-methyl 7-hydroxy-4,6-dimethyl-4-(2-trimethylsilylethoxymethoxy)hept-2-enoate

(4S,6S,8E,10E,12E)-1-(imidazol-1'-yl)-4,6,12-trimethyl-4-(2-trimethylsilylethoxymethoxy)tetradeca-8,10,12-trien-1-one

(4S,6S,8E,10E,12E)-1-(imidazol-1'-yl)-4,6,12-trimethyl-4-(2-trimethylsilylethoxymethoxy)tetradeca-8,10,12-trien-1-one

(4R,6R,2E)-methyl 7-(dimethyl-t-butylsiloxy)-4,6-dimethyl-4-(2-trimethylsilylethoxymethoxy)hept-2-enoate

(4R,6R,2E)-methyl 7-(dimethyl-t-butylsiloxy)-4,6-dimethyl-4-(2-trimethylsilylethoxymethoxy)hept-2-enoate

(4S,6S,8E,10E,12E)-1-(imidazol-1'-yl)-4,6,12-trimethyl-4-(2-trimethylsilylethoxymethoxy)tetradeca-8,10,12-trien-1-one

(4S,6S,8E,10E,12E)-1-(imidazol-1'-yl)-4,6,12-trimethyl-4-(2-trimethylsilylethoxymethoxy)tetradeca-8,10,12-trien-1-one

(2E,4R)-ethyl 5-((tert-butyldimethylsilyl)oxy)-2,4-dimethylpent-2-enoate

(2E,4R)-ethyl 5-((tert-butyldimethylsilyl)oxy)-2,4-dimethylpent-2-enoate

(4S,6S,8E,10E,12E)-1-(imidazol-1'-yl)-4,6,12-trimethyl-4-(2-trimethylsilylethoxymethoxy)tetradeca-8,10,12-trien-1-one

(4S,6S,8E,10E,12E)-1-(imidazol-1'-yl)-4,6,12-trimethyl-4-(2-trimethylsilylethoxymethoxy)tetradeca-8,10,12-trien-1-one

上游原料

(2R,4R)-5-(dimethyl-t-butylsiloxy)-2-hydroxy-2,4-dimethylpentanal (4R,6R,2E)-methyl 7-hydroxy-4,6-dimethyl-4-(2-trimethylsilylethoxymethoxy)hept-2-enoate (2R,4R)-5-(dimethyl-t-butylsiloxy)-2,4-dimethylpentane-1,2-diol (4R,6R,2E)-methyl 7-(dimethyl-t-butylsiloxy)-4,6-dimethyl-4-(2-trimethylsilylethoxymethoxy)hept-2-enoate (4R,6R,2E)-methyl 7-(dimethyl-t-butylsiloxy)-4-hydroxy-4,6-dimethylhept-2-enoate (2E,4R)-ethyl 5-((tert-butyldimethylsilyl)oxy)-2,4-dimethylpent-2-enoate

下游产品

细胞松弛素H