百科

4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-methyloxolan-2-yl]pyrimidin-2-one

4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-methyloxolan-2-yl]pyrimidin-2-one

CAS号：105281-07-0

英文名：4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-methyloxolan-2-yl]pyrimidin-2-one

分子式：C9H12FN3O3

分子量：229.208

合成路线

1-(2,5-dideoxy-2-fluoro-5-iodo-β-D-arabinofuranosyl)-5-iodocytosine

1-(2,5-dideoxy-2-fluoro-5-iodo-β-D-arabinofuranosyl)-5-iodocytosine

4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-methyloxolan-2-yl]pyrimidin-2-one

4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-methyloxolan-2-yl]pyrimidin-2-one

非西他滨

4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-methyloxolan-2-yl]pyrimidin-2-one

4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-methyloxolan-2-yl]pyrimidin-2-one

上游原料

1-(2,5-dideoxy-2-fluoro-5-iodo-β-D-arabinofuranosyl)-5-iodocytosine 非西他滨

下游产品

4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-methyloxolan-2-yl]-5-iodopyrimidin-2-one