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(3S,4R)-1-甲基-4-(4-氟苯基)-3-哌啶甲醇

(3S,4R)-1-甲基-4-(4-氟苯基)-3-哌啶甲醇

CAS号：105812-81-5

英文名：(3S,4R)-4-(4-Fluorophenyl)-3-Hydroxymethyl-1-Methylpiperidine

分子式：C13H18FNO

分子量：223.287

合成路线

(-)-(3S,4R)-4-(4-fluoro-phenyl)-1-methyl-piperidine-3-carboxylic acid methyl ester

(-)-(3S,4R)-4-(4-fluoro-phenyl)-1-methyl-piperidine-3-carboxylic acid methyl ester

(3S,4R)-1-甲基-4-(4-氟苯基)-3-哌啶甲醇

(3S,4R)-1-甲基-4-(4-氟苯基)-3-哌啶甲醇

(3S,4R)-3-ethoxycarbonyl-4-(4-fluorophenyl)-N-methylpiperidine-2,6-dione

(3S,4R)-3-ethoxycarbonyl-4-(4-fluorophenyl)-N-methylpiperidine-2,6-dione

(3S,4R)-1-甲基-4-(4-氟苯基)-3-哌啶甲醇

(3S,4R)-1-甲基-4-(4-氟苯基)-3-哌啶甲醇

(+/-)-trans-4-(4-fluorophenyl)-1-methyl-2,6-dioxo-piperidine-3-carboxylic acid ethyl ester

(+/-)-trans-4-(4-fluorophenyl)-1-methyl-2,6-dioxo-piperidine-3-carboxylic acid ethyl ester

(3S,4R)-1-甲基-4-(4-氟苯基)-3-哌啶甲醇

(3S,4R)-1-甲基-4-(4-氟苯基)-3-哌啶甲醇

对氟肉桂酸

对氟肉桂酸

(3S,4R)-1-甲基-4-(4-氟苯基)-3-哌啶甲醇

(3S,4R)-1-甲基-4-(4-氟苯基)-3-哌啶甲醇

上游原料

对氟肉桂酸 (+/-)-trans-4-(4-fluorophenyl)-1-methyl-2,6-dioxo-piperidine-3-carboxylic acid ethyl ester (-)-(3S,4R)-4-(4-fluoro-phenyl)-1-methyl-piperidine-3-carboxylic acid methyl ester (3S,4R)-3-ethoxycarbonyl-4-(4-fluorophenyl)-N-methylpiperidine-2,6-dione

下游产品

帕罗醇甲烷磺酸酯帕罗西汀 (3S,4R)-3-{[4-(苄氧基)-3-甲氧基苯氧基]甲基}-4-(4-氟苯基)-1-甲基哌啶 4-(4-氟苯)-1-甲基-3-[(4-甲苯磺酰氧基)甲基]哌啶盐酸帕罗西汀 N-甲基帕罗西汀