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2-((2R,3R,4R,5S,6R)-4-(dimethylamino)-3,5,6-tris(methoxymethoxy)-2-methyltetrahydro-2H-pyran-2-yl)-5,8-dimethoxynaphthalene-1,4-diol

2-((2R,3R,4R,5S,6R)-4-(dimethylamino)-3,5,6-tris(methoxymethoxy)-2-methyltetrahydro-2H-pyran-2-yl)-5,8-dimethoxynaphthalene-1,4-diol

CAS号：105827-56-3

英文名：2-((2R,3R,4R,5S,6R)-4-(dimethylamino)-3,5,6-tris(methoxymethoxy)-2-methyltetrahydro-2H-pyran-2-yl)-5,8-dimethoxynaphthalene-1,4-diol

分子式：C26H39NO11

分子量：541.588

合成路线

(2R,3R,4S,5S)-(-)-6-(tert-butyldimethylsilyloxy)-4-(N-methoxycarbonyl-N-methylamino)-3,5-bis(methoxymethyloxy)-2-(1,4,5,8-tetramethoxy-2-naphthalenyl)-2-hexanol

(2R,3R,4S,5S)-(-)-6-(tert-butyldimethylsilyloxy)-4-(N-methoxycarbonyl-N-methylamino)-3,5-bis(methoxymethyloxy)-2-(1,4,5,8-tetramethoxy-2-naphthalenyl)-2-hexanol

2-((2R,3R,4R,5S,6R)-4-(dimethylamino)-3,5,6-tris(methoxymethoxy)-2-methyltetrahydro-2H-pyran-2-yl)-5,8-dimethoxynaphthalene-1,4-diol

2-((2R,3R,4R,5S,6R)-4-(dimethylamino)-3,5,6-tris(methoxymethoxy)-2-methyltetrahydro-2H-pyran-2-yl)-5,8-dimethoxynaphthalene-1,4-diol

(2S,3S,4R,5R)-(-)-3-(N-methoxycarbonyl-N-methylamino)-2,4-bis(methoxymethyloxy)-5-(1,4,5,8-tetramethoxy-2-naphthalenyl)-1,5-hexanediol

(2S,3S,4R,5R)-(-)-3-(N-methoxycarbonyl-N-methylamino)-2,4-bis(methoxymethyloxy)-5-(1,4,5,8-tetramethoxy-2-naphthalenyl)-1,5-hexanediol

2-((2R,3R,4R,5S,6R)-4-(dimethylamino)-3,5,6-tris(methoxymethoxy)-2-methyltetrahydro-2H-pyran-2-yl)-5,8-dimethoxynaphthalene-1,4-diol

2-((2R,3R,4R,5S,6R)-4-(dimethylamino)-3,5,6-tris(methoxymethoxy)-2-methyltetrahydro-2H-pyran-2-yl)-5,8-dimethoxynaphthalene-1,4-diol

(3S,4R,5R,6R)-4-(N-methoxycarbonyl-N-methylamino)-3,5-bis(methoxymethyloxy)-6-methyl-6-(1,4,5,8-tetramethoxy-2-naphthalenyl)tetrahydro-2-pyranone

(3S,4R,5R,6R)-4-(N-methoxycarbonyl-N-methylamino)-3,5-bis(methoxymethyloxy)-6-methyl-6-(1,4,5,8-tetramethoxy-2-naphthalenyl)tetrahydro-2-pyranone

2-((2R,3R,4R,5S,6R)-4-(dimethylamino)-3,5,6-tris(methoxymethoxy)-2-methyltetrahydro-2H-pyran-2-yl)-5,8-dimethoxynaphthalene-1,4-diol

2-((2R,3R,4R,5S,6R)-4-(dimethylamino)-3,5,6-tris(methoxymethoxy)-2-methyltetrahydro-2H-pyran-2-yl)-5,8-dimethoxynaphthalene-1,4-diol

(2R,3R,4R,5S,6R)-(-)-4-(N-methoxycarbonyl-N-methylamino)-3,5,6-tris(methoxymethyloxy)-2-methyl-2-(1,4,5,8-tetramethoxy-2-naphthalenyl)tetrahydropyran

(2R,3R,4R,5S,6R)-(-)-4-(N-methoxycarbonyl-N-methylamino)-3,5,6-tris(methoxymethyloxy)-2-methyl-2-(1,4,5,8-tetramethoxy-2-naphthalenyl)tetrahydropyran

2-((2R,3R,4R,5S,6R)-4-(dimethylamino)-3,5,6-tris(methoxymethoxy)-2-methyltetrahydro-2H-pyran-2-yl)-5,8-dimethoxynaphthalene-1,4-diol

2-((2R,3R,4R,5S,6R)-4-(dimethylamino)-3,5,6-tris(methoxymethoxy)-2-methyltetrahydro-2H-pyran-2-yl)-5,8-dimethoxynaphthalene-1,4-diol

(2R,3R,4R,5S,6R)-(-)-4-dimethylamino-3,5,6-tris(methoxymethyloxy)-2-methyl-2-(1,4,5,8-tetramethoxy-2-naphthalenyl)tetrahydropyran

(2R,3R,4R,5S,6R)-(-)-4-dimethylamino-3,5,6-tris(methoxymethyloxy)-2-methyl-2-(1,4,5,8-tetramethoxy-2-naphthalenyl)tetrahydropyran

2-((2R,3R,4R,5S,6R)-4-(dimethylamino)-3,5,6-tris(methoxymethoxy)-2-methyltetrahydro-2H-pyran-2-yl)-5,8-dimethoxynaphthalene-1,4-diol

2-((2R,3R,4R,5S,6R)-4-(dimethylamino)-3,5,6-tris(methoxymethoxy)-2-methyltetrahydro-2H-pyran-2-yl)-5,8-dimethoxynaphthalene-1,4-diol

(2R,3R,4R,5S,6S)-(+)-6-hydroxy-4-(N-methoxycarbonyl-N-methylamino)-3,5-bis(methoxymethyloxy)-2-methyl-2-(1,4,5,8-tetramethoxy-2-naphthalenyl)tetrahydropyran

(2R,3R,4R,5S,6S)-(+)-6-hydroxy-4-(N-methoxycarbonyl-N-methylamino)-3,5-bis(methoxymethyloxy)-2-methyl-2-(1,4,5,8-tetramethoxy-2-naphthalenyl)tetrahydropyran

2-((2R,3R,4R,5S,6R)-4-(dimethylamino)-3,5,6-tris(methoxymethoxy)-2-methyltetrahydro-2H-pyran-2-yl)-5,8-dimethoxynaphthalene-1,4-diol

2-((2R,3R,4R,5S,6R)-4-(dimethylamino)-3,5,6-tris(methoxymethoxy)-2-methyltetrahydro-2H-pyran-2-yl)-5,8-dimethoxynaphthalene-1,4-diol

(2R,3R,4R,5S,6R)-(+)-2-(5,8-dimethoxy-1,4-dioxo-2-naphthalenyl)-4-dimethylamino-3,5,6-tris(methoxymethyloxy)-2-methyltetrahydropyran

(2R,3R,4R,5S,6R)-(+)-2-(5,8-dimethoxy-1,4-dioxo-2-naphthalenyl)-4-dimethylamino-3,5,6-tris(methoxymethyloxy)-2-methyltetrahydropyran

2-((2R,3R,4R,5S,6R)-4-(dimethylamino)-3,5,6-tris(methoxymethoxy)-2-methyltetrahydro-2H-pyran-2-yl)-5,8-dimethoxynaphthalene-1,4-diol

2-((2R,3R,4R,5S,6R)-4-(dimethylamino)-3,5,6-tris(methoxymethoxy)-2-methyltetrahydro-2H-pyran-2-yl)-5,8-dimethoxynaphthalene-1,4-diol

上游原料

(2R,3R,4S,5S)-(-)-6-(tert-butyldimethylsilyloxy)-4-(N-methoxycarbonyl-N-methylamino)-3,5-bis(methoxymethyloxy)-2-(1,4,5,8-tetramethoxy-2-naphthalenyl)-2-hexanol (2R,3R,4R,5S,6R)-(-)-4-(N-methoxycarbonyl-N-methylamino)-3,5,6-tris(methoxymethyloxy)-2-methyl-2-(1,4,5,8-tetramethoxy-2-naphthalenyl)tetrahydropyran (2R,3R,4R,5S,6R)-(+)-2-(5,8-dimethoxy-1,4-dioxo-2-naphthalenyl)-4-dimethylamino-3,5,6-tris(methoxymethyloxy)-2-methyltetrahydropyran (2R,3R,4R,5S,6S)-(+)-6-hydroxy-4-(N-methoxycarbonyl-N-methylamino)-3,5-bis(methoxymethyloxy)-2-methyl-2-(1,4,5,8-tetramethoxy-2-naphthalenyl)tetrahydropyran (2R,3R,4R,5S,6R)-(-)-4-dimethylamino-3,5,6-tris(methoxymethyloxy)-2-methyl-2-(1,4,5,8-tetramethoxy-2-naphthalenyl)tetrahydropyran (2S,3S,4R,5R)-(-)-3-(N-methoxycarbonyl-N-methylamino)-2,4-bis(methoxymethyloxy)-5-(1,4,5,8-tetramethoxy-2-naphthalenyl)-1,5-hexanediol (3S,4R,5R,6R)-4-(N-methoxycarbonyl-N-methylamino)-3,5-bis(methoxymethyloxy)-6-methyl-6-(1,4,5,8-tetramethoxy-2-naphthalenyl)tetrahydro-2-pyranone

下游产品

(2R,3S,4R,5R,6R)-(+)-3,5-diacetoxy-9,12-dimethoxy-4-dimethylamino-8-hydroxy-6-methyl-2,6-epoxy-3,4,5,6-tetrahydro-2H-naphthaleno[1,2-b]oxocine Nogarene (2R,3S,4R,5R,6R)-(+)-3,5-diacetoxy-4-dimethylamino-8-hydroxy-6-methyl-2,6-epoxy-3,4,5,6-tetrahydro-2H-naphthaleno[1,2-b]oxocine-9,12-dione