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(6E,10E,12E)-(5S,14S,15S)-5,14,15-Trihydroxy-icosa-6,10,12-trien-8-ynoic acid methyl ester

(6E,10E,12E)-(5S,14S,15S)-5,14,15-Trihydroxy-icosa-6,10,12-trien-8-ynoic acid methyl ester

CAS号：106062-80-0

英文名：(6E,10E,12E)-(5S,14S,15S)-5,14,15-Trihydroxy-icosa-6,10,12-trien-8-ynoic acid methyl ester

分子式：C21H32O5

分子量：364.476

合成路线

(3E,5E)-(7R,8S)-7,8-Bis-(tert-butyl-dimethyl-silanyloxy)-trideca-3,5-dien-1-yne

(3E,5E)-(7R,8S)-7,8-Bis-(tert-butyl-dimethyl-silanyloxy)-trideca-3,5-dien-1-yne

(6E,10E,12E)-(5S,14S,15S)-5,14,15-Trihydroxy-icosa-6,10,12-trien-8-ynoic acid methyl ester

(6E,10E,12E)-(5S,14S,15S)-5,14,15-Trihydroxy-icosa-6,10,12-trien-8-ynoic acid methyl ester

(6E,10E,12E)-(5S,14R,15S)-5,14,15-Tris-(tert-butyl-dimethyl-silanyloxy)-icosa-6,10,12-trien-8-ynoic acid methyl ester

(6E,10E,12E)-(5S,14R,15S)-5,14,15-Tris-(tert-butyl-dimethyl-silanyloxy)-icosa-6,10,12-trien-8-ynoic acid methyl ester

(6E,10E,12E)-(5S,14S,15S)-5,14,15-Trihydroxy-icosa-6,10,12-trien-8-ynoic acid methyl ester

(6E,10E,12E)-(5S,14S,15S)-5,14,15-Trihydroxy-icosa-6,10,12-trien-8-ynoic acid methyl ester

(6E,10E,12E)-(5S,14S,15S)-5,14,15-Tris-(tert-butyl-dimethyl-silanyloxy)-icosa-6,10,12-trien-8-ynoic acid methyl ester

(6E,10E,12E)-(5S,14S,15S)-5,14,15-Tris-(tert-butyl-dimethyl-silanyloxy)-icosa-6,10,12-trien-8-ynoic acid methyl ester

(6E,10E,12E)-(5S,14S,15S)-5,14,15-Trihydroxy-icosa-6,10,12-trien-8-ynoic acid methyl ester

(6E,10E,12E)-(5S,14S,15S)-5,14,15-Trihydroxy-icosa-6,10,12-trien-8-ynoic acid methyl ester

(3E,5Z)-(7S,8S)-7,8-Bis-(tert-butyl-dimethyl-silanyloxy)-1-trimethylsilanyl-trideca-3,5-dien-1-yne

(3E,5Z)-(7S,8S)-7,8-Bis-(tert-butyl-dimethyl-silanyloxy)-1-trimethylsilanyl-trideca-3,5-dien-1-yne

(6E,10E,12E)-(5S,14S,15S)-5,14,15-Trihydroxy-icosa-6,10,12-trien-8-ynoic acid methyl ester

(6E,10E,12E)-(5S,14S,15S)-5,14,15-Trihydroxy-icosa-6,10,12-trien-8-ynoic acid methyl ester

(3E,5E)-(7R,8S)-7,8-Bis-(tert-butyl-dimethyl-silanyloxy)-1-trimethylsilanyl-trideca-3,5-dien-1-yne

(3E,5E)-(7R,8S)-7,8-Bis-(tert-butyl-dimethyl-silanyloxy)-1-trimethylsilanyl-trideca-3,5-dien-1-yne

(6E,10E,12E)-(5S,14S,15S)-5,14,15-Trihydroxy-icosa-6,10,12-trien-8-ynoic acid methyl ester

(6E,10E,12E)-(5S,14S,15S)-5,14,15-Trihydroxy-icosa-6,10,12-trien-8-ynoic acid methyl ester

上游原料

(3E,5Z)-(7S,8S)-7,8-Bis-(tert-butyl-dimethyl-silanyloxy)-1-trimethylsilanyl-trideca-3,5-dien-1-yne (3E,5E)-(7R,8S)-7,8-Bis-(tert-butyl-dimethyl-silanyloxy)-1-trimethylsilanyl-trideca-3,5-dien-1-yne (6E,10E,12E)-(5S,14R,15S)-5,14,15-Tris-(tert-butyl-dimethyl-silanyloxy)-icosa-6,10,12-trien-8-ynoic acid methyl ester (3E,5E)-(7R,8S)-7,8-Bis-(tert-butyl-dimethyl-silanyloxy)-trideca-3,5-dien-1-yne (6E,10E,12E)-(5S,14S,15S)-5,14,15-Tris-(tert-butyl-dimethyl-silanyloxy)-icosa-6,10,12-trien-8-ynoic acid methyl ester

下游产品

14-epi-LXB4 (5S,14S,15S)-5,14,15-Trihydroxy-(6E,8Z,10E,12E)-icosa-6,8,10,12-tetraenoic methyl ester (5S,14S,15S)-5,14,15-Trihydroxy-(6E,8E,10E,12E)-icosa-6,8,10,12-tetraenoic methyl ester