百科

盐酸格拉司琼

CAS号：107007-99-8

英文名：Granisetron hydrochloride

分子式

C18H25ClN4O

熔点

290-292°C

密度

1.33g/cm3

分子量

348.87

沸点

532ºC at 760mmHg

溶解度

信号词

危险品标志

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化合物简介

A specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptor

基本信息

中文名称

盐酸格拉司琼

英文名称

Granisetron hydrochloride

中文别名

1-甲基-N-[内向-9-甲基-9-氮杂双环(3,3,1)壬烷-3-基]-lH-吲唑-3-甲酰胺盐酸盐、N-(内-9-甲基-9-氮杂二环[3,3,1]壬-3-基)-吲哚-3-羧酰胺盐酸盐、1-甲基-N-[内向-9-甲基-9-氮杂双环[3.3.1]壬烷-3-基]-1H-吲唑-3-甲酰胺盐酸盐、格拉司琼盐酸盐、桥-N-(9-甲基-9-氯杂二环[3.3.1]壬-3-基)-1-甲基-1H-吲唑-3-羧酰胺盐酸盐、1-甲基-N-[(3-endo)-9-甲基-9-氮杂双环[3.3.1]壬-3-基]-1H-吲哚-3-甲酰胺盐酸盐

英文别名

1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide、1-methyl-N-[(1S,5R)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide,hydrochloride、Granisetron Hydrochloride

CAS号

107007-99-8

分子式

C18H25ClN4O

分子量

348.87

精确质量

348.172

PSA

50.16

LOGP

3.4492