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tert-butyl (3R,4S)-3-{[[3-[(4-cyanobenzyl)oxy]-5-(3-methoxypropyl)benzyl](cyclopropyl)amino]carbonyl}-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate

CAS号：1087347-42-9

英文名：tert-butyl (3R,4S)-3-{[[3-[(4-cyanobenzyl)oxy]-5-(3-methoxypropyl)benzyl](cyclopropyl)amino]carbonyl}-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate

分子式：C48H55Cl2N3O7

分子量：856.872

合成路线

877995-77-2

1-(4-bromophenoxy)-2-(2,6-dichloro-4-methylphenoxy)ethane

1087347-42-9

tert-butyl (3R,4S)-3-{[[3-[(4-cyanobenzyl)oxy]-5-(3-methoxypropyl)benzyl](cyclopropyl)amino]carbonyl}-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate

1026786-84-4

3-hydroxy-5-[(1E)-3-(methyloxy)-1-propen-1-yl]benzaldehyde

1087347-42-9

tert-butyl (3R,4S)-3-{[[3-[(4-cyanobenzyl)oxy]-5-(3-methoxypropyl)benzyl](cyclopropyl)amino]carbonyl}-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate

1026786-89-9

[(3-{[(tert-butyl)(dimethyl)silyl]oxy}-5-{(1E)-3-methoxyprop-1-en-1-yl}benzyl)amino]cyclopropane

1087347-42-9

tert-butyl (3R,4S)-3-{[[3-[(4-cyanobenzyl)oxy]-5-(3-methoxypropyl)benzyl](cyclopropyl)amino]carbonyl}-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate

930798-40-6

(4-[2-(2,6-dichloro-4-methyl-phenoxy)ethoxy]phenyl)-boronic acid

1087347-42-9

tert-butyl (3R,4S)-3-{[[3-[(4-cyanobenzyl)oxy]-5-(3-methoxypropyl)benzyl](cyclopropyl)amino]carbonyl}-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate

176525-98-7

1-(1,1-dimethylethyl) 3-ethyl 4-{[(trifluoromethyl)sulfonyl]oxy}-1,2,5,6-tetrahydropyridine-1,3-dicarboxylate

1087347-42-9

tert-butyl (3R,4S)-3-{[[3-[(4-cyanobenzyl)oxy]-5-(3-methoxypropyl)benzyl](cyclopropyl)amino]carbonyl}-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate

921630-48-0

[(3-{[(tert-butyl)(dimethyl)silyl]oxy}-5-{3-methoxypropyl}benzyl)amino]cyclopropane

1087347-42-9

tert-butyl (3R,4S)-3-{[[3-[(4-cyanobenzyl)oxy]-5-(3-methoxypropyl)benzyl](cyclopropyl)amino]carbonyl}-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate

946003-24-3

(3R,4S)-4-{4-[2-(2,6-Dichloro-4-methyl-phenoxy)-ethoxy]-phenyl}-piperidine-1,3-dicarboxylic acid 1-tert-butyl ester

1087347-42-9

tert-butyl (3R,4S)-3-{[[3-[(4-cyanobenzyl)oxy]-5-(3-methoxypropyl)benzyl](cyclopropyl)amino]carbonyl}-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate

1026786-65-1

1-(tert-butyl) 3-ethyl (3R,4S)-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1,3-dicarboxylate

1087347-42-9

tert-butyl (3R,4S)-3-{[[3-[(4-cyanobenzyl)oxy]-5-(3-methoxypropyl)benzyl](cyclopropyl)amino]carbonyl}-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate

1026786-61-7

1-(tert-butyl) 3-ethyl 4-{4-[2-(2.6-dichloro-4-methylphenoxy)ethoxy]phenyl}-1,2,5,6-tetrahydropyridine-1,3-dicarboxylate

1087347-42-9

tert-butyl (3R,4S)-3-{[[3-[(4-cyanobenzyl)oxy]-5-(3-methoxypropyl)benzyl](cyclopropyl)amino]carbonyl}-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate

1026786-63-9

1-(tert-butyl) 3-ethyl 4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1,3-dicarboxylate

1087347-42-9

tert-butyl (3R,4S)-3-{[[3-[(4-cyanobenzyl)oxy]-5-(3-methoxypropyl)benzyl](cyclopropyl)amino]carbonyl}-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate

上游原料

1-(tert-butyl) 3-ethyl 4-{4-[2-(2.6-dichloro-4-methylphenoxy)ethoxy]phenyl}-1,2,5,6-tetrahydropyridine-1,3-dicarboxylate 1-(tert-butyl) 3-ethyl 4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1,3-dicarboxylate 3-((tert-butyl(dimethyl)silyl)oxy)-5-[(1E)-3-methoxy-prop-1-en-1-yl]-benzaldehyde (4-[2-(2,6-dichloro-4-methyl-phenoxy)ethoxy]phenyl)-boronic acid 1-(1,1-dimethylethyl) 3-ethyl 4-{[(trifluoromethyl)sulfonyl]oxy}-1,2,5,6-tetrahydropyridine-1,3-dicarboxylate tert-butyl (3R,4S)-3-({[3-{[(tert-butyl)(dimethyl)silyl]oxy}-5-(3-methoxypropyl)benzyl](cyclopropyl)amino}carbonyl)-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate 1-(4-bromophenoxy)-2-(2,6-dichloro-4-methylphenoxy)ethane [(3-{[(tert-butyl)(dimethyl)silyl]oxy}-5-{(1E)-3-methoxyprop-1-en-1-yl}benzyl)amino]cyclopropane [(3-{[(tert-butyl)(dimethyl)silyl]oxy}-5-{3-methoxypropyl}benzyl)amino]cyclopropane 1-(tert-butyl) 3-ethyl (3R,4S)-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1,3-dicarboxylate 3-hydroxy-5-[(1E)-3-(methyloxy)-1-propen-1-yl]benzaldehyde (3R,4S)-4-{4-[2-(2,6-Dichloro-4-methyl-phenoxy)-ethoxy]-phenyl}-piperidine-1,3-dicarboxylic acid 1-tert-butyl ester

下游产品

tert-butyl (3R,4S)-3-{[(cyclopropyl)(3-(3-methoxypropyl)-5-{[4-(1H-tetrazol-5-yl)benzyl]oxy}benzyl)amino]carbonyl}-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-1-carboxylate