(4R)-tert-butyl 6-tert-butyldimethylsilyloxymethyl-4-cyclopropyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate

(4R)-tert-butyl 6-tert-butyldimethylsilyloxymethyl-4-cyclopropyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate

CAS号：1087348-68-2

英文名：(4R)-tert-butyl 6-tert-butyldimethylsilyloxymethyl-4-cyclopropyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate

分子式：C20H35N3O3Si

分子量：393.596

合成路线

(5S)-methyl 5-cyclopropyl-5-((R)-1,1-dimethylethylsulfinamido)-3-oxopentanoate

(5S)-methyl 5-cyclopropyl-5-((R)-1,1-dimethylethylsulfinamido)-3-oxopentanoate

(4R)-tert-butyl 6-tert-butyldimethylsilyloxymethyl-4-cyclopropyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate

(4R)-tert-butyl 6-tert-butyldimethylsilyloxymethyl-4-cyclopropyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate

(5S)-methyl 5-cyclopropyl-2-diazo-5-((R)-1,1-dimethylethylsulfinamido)-3-oxopentanoate

(5S)-methyl 5-cyclopropyl-2-diazo-5-((R)-1,1-dimethylethylsulfinamido)-3-oxopentanoate

(4R)-tert-butyl 6-tert-butyldimethylsilyloxymethyl-4-cyclopropyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate

(4R)-tert-butyl 6-tert-butyldimethylsilyloxymethyl-4-cyclopropyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate

(S)-methyl 5-tert-butoxycarbonylamino-5-cyclopropyl-2-diazo-3-oxopentanoate

(S)-methyl 5-tert-butoxycarbonylamino-5-cyclopropyl-2-diazo-3-oxopentanoate

(4R)-tert-butyl 6-tert-butyldimethylsilyloxymethyl-4-cyclopropyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate

(4R)-tert-butyl 6-tert-butyldimethylsilyloxymethyl-4-cyclopropyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate

(5S)-tert-butyl 5-cyclopropyl-3-hydroxy-2-hydroxymethylpyrrolidine-1-carboxylate

(5S)-tert-butyl 5-cyclopropyl-3-hydroxy-2-hydroxymethylpyrrolidine-1-carboxylate

(4R)-tert-butyl 6-tert-butyldimethylsilyloxymethyl-4-cyclopropyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate

(4R)-tert-butyl 6-tert-butyldimethylsilyloxymethyl-4-cyclopropyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate

(5S)-1-tert-butyl 2-methyl 5-cyclopropyl-3-oxopyrrolidine-1,2-dicarboxylate

(5S)-1-tert-butyl 2-methyl 5-cyclopropyl-3-oxopyrrolidine-1,2-dicarboxylate

(4R)-tert-butyl 6-tert-butyldimethylsilyloxymethyl-4-cyclopropyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate

(4R)-tert-butyl 6-tert-butyldimethylsilyloxymethyl-4-cyclopropyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate

(5S)-tert-butyl 2-tert-butyldimethylsilyloxymethyl-5-cyclopropyl-3-hydroxypyrrolidine-1-carboxylate

(5S)-tert-butyl 2-tert-butyldimethylsilyloxymethyl-5-cyclopropyl-3-hydroxypyrrolidine-1-carboxylate

(4R)-tert-butyl 6-tert-butyldimethylsilyloxymethyl-4-cyclopropyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate

(4R)-tert-butyl 6-tert-butyldimethylsilyloxymethyl-4-cyclopropyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate

上游原料

(5S)-methyl 5-cyclopropyl-2-diazo-5-((R)-1,1-dimethylethylsulfinamido)-3-oxopentanoate (S)-methyl 5-tert-butoxycarbonylamino-5-cyclopropyl-2-diazo-3-oxopentanoate (5S)-1-tert-butyl 2-methyl 5-cyclopropyl-3-oxopyrrolidine-1,2-dicarboxylate (5S)-tert-butyl 5-cyclopropyl-3-hydroxy-2-hydroxymethylpyrrolidine-1-carboxylate (5S)-methyl 5-cyclopropyl-5-((R)-1,1-dimethylethylsulfinamido)-3-oxopentanoate (5S)-tert-butyl 2-tert-butyldimethylsilyloxymethyl-5-cyclopropyl-3-hydroxypyrrolidine-1-carboxylate

下游产品

((4R)-4-cyclopropyl-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-6-yl)methanol