百科

L-䓝基乙醛酸酯水合物

CAS号：111969-64-3

英文名：L-Menthyl glyoxylate hydrate

分子式

C12H22O4

熔点

80-81 °C

密度

1.09

分子量

230.301

沸点

320 °C

溶解度

信号词

危险品标志

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化合物简介

L-Menthyl 2,2-Dihydroxyacetate is used as a reagent in the synthesis of Lamivudine; a potent nucleoside reverse transcriptase inhibitor used for the treatment of chronic hepatitis B. L-Menthyl 2,2-Dihydroxyacetate is also used as a reagent in the synthesis of 4-acetoxy-3-hydroxyethylazetidin-2-one, a key intermediate for the preparation of penem and carbapenem antibiotics.

基本信息

中文名称

L-䓝基乙醛酸酯水合物

英文名称

L-Menthyl glyoxylate hydrate

中文别名

乙醛酸薄荷酯水合物、L-孟基乙醛酸酯水合物、水合乙醛酸薄荷酯、拉米夫定中间体L-MGH、2,2-二羟基醋酸-(1R,2S,5R)-2-异丙基-5-甲基环己酯、(1S)-(+)-孟基乙醛酸水合物、䓝基乙醛酸水合物、5-甲基-2-异丙基环己醇二羟基乙酸酯

英文别名

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 2,2-Dihydroxyacetate、(1R)-(-)-Menthyl glyoxylate monohydrate、L-menthyl glyoxylate、2,2-Dihydroxyacetic acid (-)-menthyl ester、L-MENTHYL 2,2-DIHYDROXYACETATE、L-Menthyl glyoxylate monohydrate、(-)-menthyl glyoxylate hydrate、L-Menthyl Glyoxylate Hydrate、2,2-Dihydroxyacetic Acid (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl Ester、Glyoxylic acid (1S)-menthyl ester hydrate、(-)-Menthyl 2,2-Dihydroxyacetate、L-MGH、Acetic acid, dihydroxy-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester、Acetic acid, dihydroxy-, 5-methyl-2-(1-methylethyl)cyclohexyl ester, [1R-(1α,2β,5α)]-、2,2-Dihydroxyacetic acid, (-)-menthyl ester、Acetic acid, 2,2-dihydroxy-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester、(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl dihydroxy-acetate

CAS号

111969-64-3

分子式

C12H22O4

分子量

230.301

精确质量

230.152

PSA

66.76

LOGP

1.3011