百科

(1α,2α,3R*,14bα)-(+/-)-1,2,3,5,6,8,9,14b-octahydro-4H-cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepine-1,2-diol

(1α,2α,3R*,14bα)-(+/-)-1,2,3,5,6,8,9,14b-octahydro-4H-cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepine-1,2-diol

CAS号：113668-90-9

英文名：(1α,2α,3R*,14bα)-(+/-)-1,2,3,5,6,8,9,14b-octahydro-4H-cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepine-1,2-diol

分子式：C17H21NO4

分子量：303.353

合成路线

(2S,3R)-rac-2,3-(isopropylidenedioxy)-5-(phenylsulfonyl)-4-cyclopentene

(2S,3R)-rac-2,3-(isopropylidenedioxy)-5-(phenylsulfonyl)-4-cyclopentene

(1α,2α,3R*,14bα)-(+/-)-1,2,3,5,6,8,9,14b-octahydro-4H-cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepine-1,2-diol

(1α,2α,3R*,14bα)-(+/-)-1,2,3,5,6,8,9,14b-octahydro-4H-cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepine-1,2-diol

(3aα,4aR*,15bβ,15cα)-(+/-)-3a,6,7,10,15b,15c-hexahydro-2,2-dimethyl-5H-[1,3]dioxolo[4,5-h]-1,3-dioxolo[4,5Z]cyclopenta[1,2-a]pyrrolo[2,1-b][3]benzazepin-9(4H)-one

(3aα,4aR*,15bβ,15cα)-(+/-)-3a,6,7,10,15b,15c-hexahydro-2,2-dimethyl-5H-[1,3]dioxolo[4,5-h]-1,3-dioxolo[4,5Z]cyclopenta[1,2-a]pyrrolo[2,1-b][3]benzazepin-9(4H)-one

(1α,2α,3R*,14bα)-(+/-)-1,2,3,5,6,8,9,14b-octahydro-4H-cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepine-1,2-diol

(1α,2α,3R*,14bα)-(+/-)-1,2,3,5,6,8,9,14b-octahydro-4H-cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepine-1,2-diol

上游原料

(3aα,4aR*,15bβ,15cα)-(+/-)-3a,6,7,10,15b,15c-hexahydro-2,2-dimethyl-5H-[1,3]dioxolo[4,5-h]-1,3-dioxolo[4,5Z]cyclopenta[1,2-a]pyrrolo[2,1-b][3]benzazepin-9(4H)-one (2S,3R)-rac-2,3-(isopropylidenedioxy)-5-(phenylsulfonyl)-4-cyclopentene

下游产品

(±)-三尖杉碱