百科

(2S,4aS,6aS,6bR,8aR,10R,12aS,12bR,14bS)-10-Hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydro-picene-2-carboxylic acid methyl ester

CAS号：118492-16-3

英文名：(2S,4aS,6aS,6bR,8aR,10R,12aS,12bR,14bS)-10-Hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydro-picene-2-carboxylic acid methyl ester

分子式：C31H48O4

分子量：484.71

合成路线

121687-86-3

118492-16-3

(2S,4aS,6aS,6bR,8aR,10R,12aS,12bR,14bS)-10-Hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydro-picene-2-carboxylic acid methyl ester

121687-85-2

apioglycyrrhizin dimethyl ester

118492-16-3

(2S,4aS,6aS,6bR,8aR,10R,12aS,12bR,14bS)-10-Hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydro-picene-2-carboxylic acid methyl ester

10301-74-3

3β-acetoxy-11-oxo-olean-12-en-30-oic acid methyl ester

118492-16-3

(2S,4aS,6aS,6bR,8aR,10R,12aS,12bR,14bS)-10-Hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydro-picene-2-carboxylic acid methyl ester

10527-59-0

methyl 3β-hydroxy-18β-olean-12-en-30-oate

118492-16-3

(2S,4aS,6aS,6bR,8aR,10R,12aS,12bR,14bS)-10-Hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydro-picene-2-carboxylic acid methyl ester

146236-30-8

118492-16-3

(2S,4aS,6aS,6bR,8aR,10R,12aS,12bR,14bS)-10-Hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydro-picene-2-carboxylic acid methyl ester

146236-29-5

118492-16-3

(2S,4aS,6aS,6bR,8aR,10R,12aS,12bR,14bS)-10-Hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydro-picene-2-carboxylic acid methyl ester

152832-24-1

118492-16-3

(2S,4aS,6aS,6bR,8aR,10R,12aS,12bR,14bS)-10-Hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydro-picene-2-carboxylic acid methyl ester

6277-14-1

乙酰甘草亭酸铝

118492-16-3

(2S,4aS,6aS,6bR,8aR,10R,12aS,12bR,14bS)-10-Hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydro-picene-2-carboxylic acid methyl ester

上游原料

3β-acetoxy-11-oxo-olean-12-en-30-oic acid methyl ester 乙酰甘草亭酸铝 apioglycyrrhizin dimethyl ester methyl 3β-hydroxy-18β-olean-12-en-30-oate

下游产品

methyl 2α,3α-oxido-11-oxo-18β-olean-12-en-30-oate methyl (3β)-3-(L-alanylamino)-11-oxo-olean-12-en-30-oate methyl (3β)-3-(Boc-O-methyl-L-glutamyl)-11-oxo-olean-12-en-30-oate methyl 3-O-benzyl-glycyrrhetinate methyl 3β-O-(3-O-benzyl-4,6-O-benzylidene-β-D-glucopyranosyl)-18β-glycyrrhetinate 3-O-benzyl-30-O-acetylglycyrrhetol methyl 3-O-(3,4-di-O-acetyl-2,6-dideoxy-α-L-arabino-hexopyranosyl)-3β-hydroxy-11-oxo-18β-olean-12-ene-20β-carboxylate 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide methyl 3-[6-((2L)-2-[tert-butoxycarbonylamino]propanoyl)-oxylmino]-11-oxo-olean-12-en-30-oate 11-oxo-18β-oleana-2,12-dien-30-oic acid methyl β-D-galactopyranosyl-(1->4)-β-D-glucopyranosyl-3-O-18β-glycyrrhetinate methyl 3-O-[6'-O-(methyl 2'',3'',4''-tri-O-acetyl-β-D-glucuronatopyranosyl)-2',4',6'-tri-O-acetyl-β-D-galactopyranosyl]glycyrrhetinate methyl (3β)-3-(Boc-O-methyl-L-asparagyl)-11-oxo-olean-12-en-30-oate methyl (3β)-3-(L-asparagyl)-11-oxo-olean-12-en-30-oate hydrochloride 3-O-benzylglycyrrhetol methyl (3β)-3-[2-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-4,6-di-O-benzyl-3-deoxy-3-fluoro-β-D-glucopyranosyloxy]-11-oxoolean-12-en-30-oate