化合物简介
N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-Carbamic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of bortezomib.Bortezomib is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.
基本信息
中文名称
tert-butyl [1-({(1S)-3-methyl-1-[(3aS,4S,6S,7aS)-3a,5,5-trimethylhexahydro-4,6-methano-1,3,2-benzodioxaborol-2-yl]butyl}amino)-1-oxo-3-phenylpropan-2-yl]carbamate
英文名称
tert-butyl [1-({(1S)-3-methyl-1-[(3aS,4S,6S,7aS)-3a,5,5-trimethylhexahydro-4,6-methano-1,3,2-benzodioxaborol-2-yl]butyl}amino)-1-oxo-3-phenylpropan-2-yl]carbamate
中文别名
英文别名
CAS号
1187479-72-6
分子式
C29H45BN2O5
分子量
512.489
精确质量
512.342
PSA
85.89
LOGP
6.1225