百科

1-((2R,3S,4R,5R)-3-(piperidin-1-yl)-4-tosyl-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

1-((2R,3S,4R,5R)-3-(piperidin-1-yl)-4-tosyl-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

CAS号：119753-99-0

英文名：1-((2R,3S,4R,5R)-3-(piperidin-1-yl)-4-tosyl-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

分子式：C40H41N3O6S

分子量：691.835

合成路线

1-(5'-trityl-2',3'-dideoxy-3'-toluenesulfonyl-β-D-glyceropent-2-enofuranosyl)uracil

1-(5'-trityl-2',3'-dideoxy-3'-toluenesulfonyl-β-D-glyceropent-2-enofuranosyl)uracil

1-((2R,3S,4R,5R)-3-(piperidin-1-yl)-4-tosyl-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

1-((2R,3S,4R,5R)-3-(piperidin-1-yl)-4-tosyl-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

5’-O-三苯甲基尿苷-2’,3’-来苏-环氧化物

5’-O-三苯甲基尿苷-2’,3’-来苏-环氧化物

1-((2R,3S,4R,5R)-3-(piperidin-1-yl)-4-tosyl-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

1-((2R,3S,4R,5R)-3-(piperidin-1-yl)-4-tosyl-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

1-(5'-O-trityl-3'-deoxy-3'-(4-toluene)thio-β-D-arabinofuranosyl)uracil

1-(5'-O-trityl-3'-deoxy-3'-(4-toluene)thio-β-D-arabinofuranosyl)uracil

1-((2R,3S,4R,5R)-3-(piperidin-1-yl)-4-tosyl-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

1-((2R,3S,4R,5R)-3-(piperidin-1-yl)-4-tosyl-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

1-(5'-O-trityl-3'-deoxy-3'-toluenesulfonyl-β-D-arabinofuranosyl)uracil

1-(5'-O-trityl-3'-deoxy-3'-toluenesulfonyl-β-D-arabinofuranosyl)uracil

1-((2R,3S,4R,5R)-3-(piperidin-1-yl)-4-tosyl-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

1-((2R,3S,4R,5R)-3-(piperidin-1-yl)-4-tosyl-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

1-[2,3-di-O-(metanesulfonyl)-5-O-(triphenylmethyl)-β-D-ribofuranosyl]pyrimidine-2,4(1H,3H)-dione

1-[2,3-di-O-(metanesulfonyl)-5-O-(triphenylmethyl)-β-D-ribofuranosyl]pyrimidine-2,4(1H,3H)-dione

1-((2R,3S,4R,5R)-3-(piperidin-1-yl)-4-tosyl-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

1-((2R,3S,4R,5R)-3-(piperidin-1-yl)-4-tosyl-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

上游原料

哌啶 1-(5'-O-trityl-3'-deoxy-3'-toluenesulfonyl-β-D-arabinofuranosyl)uracil 1-(5'-O-trityl-3'-deoxy-3'-(4-toluene)thio-β-D-arabinofuranosyl)uracil 1-(5'-trityl-2',3'-dideoxy-3'-toluenesulfonyl-β-D-glyceropent-2-enofuranosyl)uracil 5’-O-三苯甲基尿苷-2’,3’-来苏-环氧化物 1-[2,3-di-O-(metanesulfonyl)-5-O-(triphenylmethyl)-β-D-ribofuranosyl]pyrimidine-2,4(1H,3H)-dione

下游产品

1-[(2R,3R,5S)-5-(hydroxymethyl)-3-piperidin-1-yloxolan-2-yl]pyrimidine-2,4-dione 1-((2R,3R,5S)-3-(piperidin-1-yl)-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione