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2-((1S,3R,6S)-10-(tert-butoxycarbonyl)-3-methyl-5,14-dioxo-10-azaspiro[5.8]tetradecan-1-yl)acetic acid

2-((1S,3R,6S)-10-(tert-butoxycarbonyl)-3-methyl-5,14-dioxo-10-azaspiro[5.8]tetradecan-1-yl)acetic acid

CAS号：1207722-98-2

英文名：2-((1S,3R,6S)-10-(tert-butoxycarbonyl)-3-methyl-5,14-dioxo-10-azaspiro[5.8]tetradecan-1-yl)acetic acid

分子式：C21H33NO6

分子量：395.49

合成路线

tert-butyl (9aS,11R,13aS)-11-methyl-13-oxo-2,3,6,7,9,9a,10,11,12,13-decahydro-1H-indeno[1,7a-e]azonine-4(5H)-carboxylate

tert-butyl (9aS,11R,13aS)-11-methyl-13-oxo-2,3,6,7,9,9a,10,11,12,13-decahydro-1H-indeno[1,7a-e]azonine-4(5H)-carboxylate

2-((1S,3R,6S)-10-(tert-butoxycarbonyl)-3-methyl-5,14-dioxo-10-azaspiro[5.8]tetradecan-1-yl)acetic acid

2-((1S,3R,6S)-10-(tert-butoxycarbonyl)-3-methyl-5,14-dioxo-10-azaspiro[5.8]tetradecan-1-yl)acetic acid

tert-butyl (1R,3R,6S)-1-allyl-3-methyl-5,14-dioxo-10-azaspiro[5.8]tetradecane-10-carboxylate

tert-butyl (1R,3R,6S)-1-allyl-3-methyl-5,14-dioxo-10-azaspiro[5.8]tetradecane-10-carboxylate

2-((1S,3R,6S)-10-(tert-butoxycarbonyl)-3-methyl-5,14-dioxo-10-azaspiro[5.8]tetradecan-1-yl)acetic acid

2-((1S,3R,6S)-10-(tert-butoxycarbonyl)-3-methyl-5,14-dioxo-10-azaspiro[5.8]tetradecan-1-yl)acetic acid

tert-butyl (3-((tert-butyldiphenylsilyl)oxy)propyl)(4-hydroxybutyl)carbamate

tert-butyl (3-((tert-butyldiphenylsilyl)oxy)propyl)(4-hydroxybutyl)carbamate

2-((1S,3R,6S)-10-(tert-butoxycarbonyl)-3-methyl-5,14-dioxo-10-azaspiro[5.8]tetradecan-1-yl)acetic acid

2-((1S,3R,6S)-10-(tert-butoxycarbonyl)-3-methyl-5,14-dioxo-10-azaspiro[5.8]tetradecan-1-yl)acetic acid

(5R)-5-methylcyclohex-2-enone

(5R)-5-methylcyclohex-2-enone

2-((1S,3R,6S)-10-(tert-butoxycarbonyl)-3-methyl-5,14-dioxo-10-azaspiro[5.8]tetradecan-1-yl)acetic acid

2-((1S,3R,6S)-10-(tert-butoxycarbonyl)-3-methyl-5,14-dioxo-10-azaspiro[5.8]tetradecan-1-yl)acetic acid

上游原料

tert-butyl (9aS,11R,13aS)-11-methyl-13-oxo-2,3,6,7,9,9a,10,11,12,13-decahydro-1H-indeno[1,7a-e]azonine-4(5H)-carboxylate (5R)-5-methylcyclohex-2-enone tert-butyl (1R,3R,6S)-1-allyl-3-methyl-5,14-dioxo-10-azaspiro[5.8]tetradecane-10-carboxylate tert-butyl (3-((tert-butyldiphenylsilyl)oxy)propyl)(4-hydroxybutyl)carbamate

下游产品

(4aS,6R,8aS)-6-methyl-4a,5,6,7,10,11-hexahydro-3H,9H-benzo[e]pyrrolo[3,2,1-ij]quinoline-3,8(4H)-dione (2R,4aS,12aS)-2-methyl-6,7,9,10,12,12a-hexahydro-2H,5H-benzo[e]pyrrolo[3,2,1-ij]quinoline-4,11(1H,3H)-dione