百科

(5S,5aS,9aS,9bS)-5-(tert-butyldimethylsilyloxy)-5,5a,6,7,8,9,9a,9b-octahydro-9b-hydroxy-6,6,9a-trimethylnaphtho<1,2-c>furan-3(1H)-one

(5S,5aS,9aS,9bS)-5-(tert-butyldimethylsilyloxy)-5,5a,6,7,8,9,9a,9b-octahydro-9b-hydroxy-6,6,9a-trimethylnaphtho<1,2-c>furan-3(1H)-one

CAS号：121617-66-1

英文名：(5S,5aS,9aS,9bS)-5-(tert-butyldimethylsilyloxy)-5,5a,6,7,8,9,9a,9b-octahydro-9b-hydroxy-6,6,9a-trimethylnaphtho<1,2-c>furan-3(1H)-one

分子式：C21H36O4Si

分子量：380.594

合成路线

methyl (4S,4'S,4a'S,8a'S)-4'a,5',6',7',8',8'a-hexahydro-4'-hydroxy-5',5',8'a-trimethyl-2-oxospiro<1,3-dioxolane-4,1'(4'H)-naphthalene>-2'-carboxylate

methyl (4S,4'S,4a'S,8a'S)-4'a,5',6',7',8',8'a-hexahydro-4'-hydroxy-5',5',8'a-trimethyl-2-oxospiro<1,3-dioxolane-4,1'(4'H)-naphthalene>-2'-carboxylate

(5S,5aS,9aS,9bS)-5-(tert-butyldimethylsilyloxy)-5,5a,6,7,8,9,9a,9b-octahydro-9b-hydroxy-6,6,9a-trimethylnaphtho<1,2-c>furan-3(1H)-one

(5S,5aS,9aS,9bS)-5-(tert-butyldimethylsilyloxy)-5,5a,6,7,8,9,9a,9b-octahydro-9b-hydroxy-6,6,9a-trimethylnaphtho<1,2-c>furan-3(1H)-one

methyl (4S,4'S,4a'S,8a'S)-4'-(tert-butyldimethylsilyloxy)-4'a,5',6',7',8',8'a-hexahydro-5',5',8'a-trimethyl-2-oxospiro<1,3-dioxolane-4,1'(4'H)-naphthalene>-2'-carboxylate

methyl (4S,4'S,4a'S,8a'S)-4'-(tert-butyldimethylsilyloxy)-4'a,5',6',7',8',8'a-hexahydro-5',5',8'a-trimethyl-2-oxospiro<1,3-dioxolane-4,1'(4'H)-naphthalene>-2'-carboxylate

(5S,5aS,9aS,9bS)-5-(tert-butyldimethylsilyloxy)-5,5a,6,7,8,9,9a,9b-octahydro-9b-hydroxy-6,6,9a-trimethylnaphtho<1,2-c>furan-3(1H)-one

(5S,5aS,9aS,9bS)-5-(tert-butyldimethylsilyloxy)-5,5a,6,7,8,9,9a,9b-octahydro-9b-hydroxy-6,6,9a-trimethylnaphtho<1,2-c>furan-3(1H)-one

(4S,4a'S,8a'S)-2'-(1,3-dioxolan-2-yl)-4'a,5',6',7',8',8'a-hexahydro-5',5',8a'-trimethylspiro<1,3-dioxolane-4,1'(4'H)-naphthalene>-2-one

(4S,4a'S,8a'S)-2'-(1,3-dioxolan-2-yl)-4'a,5',6',7',8',8'a-hexahydro-5',5',8a'-trimethylspiro<1,3-dioxolane-4,1'(4'H)-naphthalene>-2-one

(5S,5aS,9aS,9bS)-5-(tert-butyldimethylsilyloxy)-5,5a,6,7,8,9,9a,9b-octahydro-9b-hydroxy-6,6,9a-trimethylnaphtho<1,2-c>furan-3(1H)-one

(5S,5aS,9aS,9bS)-5-(tert-butyldimethylsilyloxy)-5,5a,6,7,8,9,9a,9b-octahydro-9b-hydroxy-6,6,9a-trimethylnaphtho<1,2-c>furan-3(1H)-one

(1S,4aS,8aS)-5,5,8a-trimethyl-2'-oxo-4a,5,6,7,8,8a-hexahydro-4H-spiro[naphthalene-1,4'-[1,3]dioxolane]-2-carbaldehyde

(1S,4aS,8aS)-5,5,8a-trimethyl-2'-oxo-4a,5,6,7,8,8a-hexahydro-4H-spiro[naphthalene-1,4'-[1,3]dioxolane]-2-carbaldehyde

(5S,5aS,9aS,9bS)-5-(tert-butyldimethylsilyloxy)-5,5a,6,7,8,9,9a,9b-octahydro-9b-hydroxy-6,6,9a-trimethylnaphtho<1,2-c>furan-3(1H)-one

(5S,5aS,9aS,9bS)-5-(tert-butyldimethylsilyloxy)-5,5a,6,7,8,9,9a,9b-octahydro-9b-hydroxy-6,6,9a-trimethylnaphtho<1,2-c>furan-3(1H)-one

上游原料

(1S,4aS,8aS)-5,5,8a-trimethyl-2'-oxo-4a,5,6,7,8,8a-hexahydro-4H-spiro[naphthalene-1,4'-[1,3]dioxolane]-2-carbaldehyde (4S,4a'S,8a'S)-2'-(1,3-dioxolan-2-yl)-4'a,5',6',7',8',8'a-hexahydro-5',5',8a'-trimethylspiro<1,3-dioxolane-4,1'(4'H)-naphthalene>-2-one methyl (4S,4'S,4a'S,8a'S)-4'-(tert-butyldimethylsilyloxy)-4'a,5',6',7',8',8'a-hexahydro-5',5',8'a-trimethyl-2-oxospiro<1,3-dioxolane-4,1'(4'H)-naphthalene>-2'-carboxylate methyl (4S,4'S,4a'S,8a'S)-4'a,5',6',7',8',8'a-hexahydro-4'-hydroxy-5',5',8'a-trimethyl-2-oxospiro<1,3-dioxolane-4,1'(4'H)-naphthalene>-2'-carboxylate

下游产品

(1R,5R,5aS,9aS,9bS)-5-(tert-Butyl-dimethyl-silanyloxy)-6,6,9a-trimethyl-3,5,5a,6,7,8,9,9a-octahydro-naphtho[1,2-c]furan-1,9b-diol (1S,4S,4aS,8aS)-4-(tert-butyldimethylsilyloxy)-2-(tert-butyldimethylsilyloxymethyl)-1,4,4a,5,6,7,8,8a-octahydro-1-hydroxy-5,5,8a-trimethylnaphthalene-1-carboxaldehyde (1S,4S,4aS,8aS)-4-(tert-butyldimethylsilyloxy)-2-(tert-butyldimethylsilyloxymethyl)-1,4,4a,5,6,7,8,8a-octahydro-1-(hydroxymethyl)-5,5,8a-trimethylnaphthalene-1-ol