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(1S,4R,4aS,8aS)-4-(tert-Butyl-dimethyl-silanyloxy)-1,2-bis-hydroxymethyl-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-ol

(1S,4R,4aS,8aS)-4-(tert-Butyl-dimethyl-silanyloxy)-1,2-bis-hydroxymethyl-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-ol

CAS号：121617-67-2

英文名：(1S,4R,4aS,8aS)-4-(tert-Butyl-dimethyl-silanyloxy)-1,2-bis-hydroxymethyl-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-ol

分子式：C21H40O4Si

分子量：384.625

合成路线

methyl (4S,4'S,4a'S,8a'S)-4'a,5',6',7',8',8'a-hexahydro-4'-hydroxy-5',5',8'a-trimethyl-2-oxospiro<1,3-dioxolane-4,1'(4'H)-naphthalene>-2'-carboxylate

methyl (4S,4'S,4a'S,8a'S)-4'a,5',6',7',8',8'a-hexahydro-4'-hydroxy-5',5',8'a-trimethyl-2-oxospiro<1,3-dioxolane-4,1'(4'H)-naphthalene>-2'-carboxylate

(1S,4R,4aS,8aS)-4-(tert-Butyl-dimethyl-silanyloxy)-1,2-bis-hydroxymethyl-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-ol

(1S,4R,4aS,8aS)-4-(tert-Butyl-dimethyl-silanyloxy)-1,2-bis-hydroxymethyl-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-ol

methyl (4S,4'S,4a'S,8a'S)-4'-(tert-butyldimethylsilyloxy)-4'a,5',6',7',8',8'a-hexahydro-5',5',8'a-trimethyl-2-oxospiro<1,3-dioxolane-4,1'(4'H)-naphthalene>-2'-carboxylate

methyl (4S,4'S,4a'S,8a'S)-4'-(tert-butyldimethylsilyloxy)-4'a,5',6',7',8',8'a-hexahydro-5',5',8'a-trimethyl-2-oxospiro<1,3-dioxolane-4,1'(4'H)-naphthalene>-2'-carboxylate

(1S,4R,4aS,8aS)-4-(tert-Butyl-dimethyl-silanyloxy)-1,2-bis-hydroxymethyl-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-ol

(1S,4R,4aS,8aS)-4-(tert-Butyl-dimethyl-silanyloxy)-1,2-bis-hydroxymethyl-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-ol

(4S,4a'S,8a'S)-2'-(1,3-dioxolan-2-yl)-4'a,5',6',7',8',8'a-hexahydro-5',5',8a'-trimethylspiro<1,3-dioxolane-4,1'(4'H)-naphthalene>-2-one

(4S,4a'S,8a'S)-2'-(1,3-dioxolan-2-yl)-4'a,5',6',7',8',8'a-hexahydro-5',5',8a'-trimethylspiro<1,3-dioxolane-4,1'(4'H)-naphthalene>-2-one

(1S,4R,4aS,8aS)-4-(tert-Butyl-dimethyl-silanyloxy)-1,2-bis-hydroxymethyl-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-ol

(1S,4R,4aS,8aS)-4-(tert-Butyl-dimethyl-silanyloxy)-1,2-bis-hydroxymethyl-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-ol

(1S,4aS,8aS)-5,5,8a-trimethyl-2'-oxo-4a,5,6,7,8,8a-hexahydro-4H-spiro[naphthalene-1,4'-[1,3]dioxolane]-2-carbaldehyde

(1S,4aS,8aS)-5,5,8a-trimethyl-2'-oxo-4a,5,6,7,8,8a-hexahydro-4H-spiro[naphthalene-1,4'-[1,3]dioxolane]-2-carbaldehyde

(1S,4R,4aS,8aS)-4-(tert-Butyl-dimethyl-silanyloxy)-1,2-bis-hydroxymethyl-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-ol

(1S,4R,4aS,8aS)-4-(tert-Butyl-dimethyl-silanyloxy)-1,2-bis-hydroxymethyl-5,5,8a-trimethyl-1,4,4a,5,6,7,8,8a-octahydro-naphthalen-1-ol

上游原料

(1S,4aS,8aS)-5,5,8a-trimethyl-2'-oxo-4a,5,6,7,8,8a-hexahydro-4H-spiro[naphthalene-1,4'-[1,3]dioxolane]-2-carbaldehyde (4S,4a'S,8a'S)-2'-(1,3-dioxolan-2-yl)-4'a,5',6',7',8',8'a-hexahydro-5',5',8a'-trimethylspiro<1,3-dioxolane-4,1'(4'H)-naphthalene>-2-one methyl (4S,4'S,4a'S,8a'S)-4'-(tert-butyldimethylsilyloxy)-4'a,5',6',7',8',8'a-hexahydro-5',5',8'a-trimethyl-2-oxospiro<1,3-dioxolane-4,1'(4'H)-naphthalene>-2'-carboxylate methyl (4S,4'S,4a'S,8a'S)-4'a,5',6',7',8',8'a-hexahydro-4'-hydroxy-5',5',8'a-trimethyl-2-oxospiro<1,3-dioxolane-4,1'(4'H)-naphthalene>-2'-carboxylate

下游产品

(1R,5R,5aS,9aS,9bS)-5-(tert-Butyl-dimethyl-silanyloxy)-6,6,9a-trimethyl-3,5,5a,6,7,8,9,9a-octahydro-naphtho[1,2-c]furan-1,9b-diol (1S,4S,4aS,8aS)-4-(tert-butyldimethylsilyloxy)-2-(tert-butyldimethylsilyloxymethyl)-1,4,4a,5,6,7,8,8a-octahydro-1-hydroxy-5,5,8a-trimethylnaphthalene-1-carboxaldehyde