百科

(2R,3S,5R)-2-((((2,3-dimethylbutan-2-yl)dimethylsilyl)oxy)methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl methanesulfonate

CAS号：123533-04-0

英文名：(2R,3S,5R)-2-((((2,3-dimethylbutan-2-yl)dimethylsilyl)oxy)methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl methanesulfonate

分子式：C19H34N2O7SSi

分子量：462.633

合成路线

123533-02-8

5'-O-[dimethyl(1,1,2-trimethylpropyl)silyl]thymidine

124-63-0

甲烷磺酰氯

123533-04-0

(2R,3S,5R)-2-((((2,3-dimethylbutan-2-yl)dimethylsilyl)oxy)methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl methanesulfonate

上游原料

5'-O-[dimethyl(1,1,2-trimethylpropyl)silyl]thymidine 甲烷磺酰氯

下游产品

N-[(2S,3S,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]formamide 齐多夫定 3’-氨基-2’,3’-双脱氧胸苷