化合物简介
Des[2’-(1H-tetrazol-5-yl)] 2-Cyanolosartan carboxaldehyde is a derivative of Losartan carboxaldehyde. Des[2’-(1H-tetrazol-5-yl)] 2-Cyanolosartan carboxaldehyde is also used as reagent to synthesize Losartan Potassium, a an angiotensin II antagonist and is commonly used to significantly reduce risk of new onset atrial fibrillation and associated stroke in high-risk patients.
基本信息
中文名称
去[2’-(1H-四唑-5-基)]2-氰基氯沙坦甲醛
英文名称
2-n-Butyl-4-chloro-1-[(2'-cyanobiphenyl-4-yl)methyl]imidazole-5-carboxaldehyde
中文别名
英文别名
Des[2\'-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde
CAS号
124750-67-0
分子式
C22H20ClN3O
分子量
377.867
精确质量
377.129
PSA
58.68
LOGP
5.27858
编号系统
EINECS号
603-011-4
物化性质
蒸汽压
6.7E-14mmHg at 25°C