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(5S,6Z,8E,10E,12R)-5,12-bis((tert-butyldimethylsilyl)oxy)icosa-6,8,10-trien-14-ynoic acid

(5S,6Z,8E,10E,12R)-5,12-bis((tert-butyldimethylsilyl)oxy)icosa-6,8,10-trien-14-ynoic acid

CAS号：129594-44-1

英文名：(5S,6Z,8E,10E,12R)-5,12-bis((tert-butyldimethylsilyl)oxy)icosa-6,8,10-trien-14-ynoic acid

分子式：C32H58O4Si2

分子量：562.972

合成路线

溴代正戊烷

溴代正戊烷

(5S,6Z,8E,10E,12R)-5,12-bis((tert-butyldimethylsilyl)oxy)icosa-6,8,10-trien-14-ynoic acid

(5S,6Z,8E,10E,12R)-5,12-bis((tert-butyldimethylsilyl)oxy)icosa-6,8,10-trien-14-ynoic acid

4-(1'-ethoxyethoxy)-6-(trimethylsilyl)-5(E)-hexen-1-yne

4-(1'-ethoxyethoxy)-6-(trimethylsilyl)-5(E)-hexen-1-yne

(5S,6Z,8E,10E,12R)-5,12-bis((tert-butyldimethylsilyl)oxy)icosa-6,8,10-trien-14-ynoic acid

(5S,6Z,8E,10E,12R)-5,12-bis((tert-butyldimethylsilyl)oxy)icosa-6,8,10-trien-14-ynoic acid

1-(trimethylsilyl)-1(E)-undecen-5-yn-3-ol

1-(trimethylsilyl)-1(E)-undecen-5-yn-3-ol

(5S,6Z,8E,10E,12R)-5,12-bis((tert-butyldimethylsilyl)oxy)icosa-6,8,10-trien-14-ynoic acid

(5S,6Z,8E,10E,12R)-5,12-bis((tert-butyldimethylsilyl)oxy)icosa-6,8,10-trien-14-ynoic acid

Methyl (5S)-7-Bromo-5-hydroxyhept-6-enoate

Methyl (5S)-7-Bromo-5-hydroxyhept-6-enoate

(5S,6Z,8E,10E,12R)-5,12-bis((tert-butyldimethylsilyl)oxy)icosa-6,8,10-trien-14-ynoic acid

(5S,6Z,8E,10E,12R)-5,12-bis((tert-butyldimethylsilyl)oxy)icosa-6,8,10-trien-14-ynoic acid

5-氧代戊酸甲酯

5-氧代戊酸甲酯

(5S,6Z,8E,10E,12R)-5,12-bis((tert-butyldimethylsilyl)oxy)icosa-6,8,10-trien-14-ynoic acid

(5S,6Z,8E,10E,12R)-5,12-bis((tert-butyldimethylsilyl)oxy)icosa-6,8,10-trien-14-ynoic acid

上游原料

4-(1'-ethoxyethoxy)-6-(trimethylsilyl)-5(E)-hexen-1-yne 溴代正戊烷 1-(trimethylsilyl)-1(E)-undecen-5-yn-3-ol 5-氧代戊酸甲酯 Methyl (5S)-7-Bromo-5-hydroxyhept-6-enoate

下游产品

14,15-脱氢白[细胞]三烯B4