百科

benzyl (S)-2-((5-(2-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidine-2-carboxamido)quinolin-6-yl)pyrimidin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

benzyl (S)-2-((5-(2-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidine-2-carboxamido)quinolin-6-yl)pyrimidin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

CAS号：1312611-26-9

英文名：benzyl (S)-2-((5-(2-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidine-2-carboxamido)quinolin-6-yl)pyrimidin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

分子式：C38H42N8O7

分子量：722.789

合成路线

tert-butyl (S)-2-((6-bromoquinolin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

tert-butyl (S)-2-((6-bromoquinolin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

benzyl (S)-2-((5-(2-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidine-2-carboxamido)quinolin-6-yl)pyrimidin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

benzyl (S)-2-((5-(2-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidine-2-carboxamido)quinolin-6-yl)pyrimidin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

tert-butyl (S)-2-((6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinolin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

tert-butyl (S)-2-((6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinolin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

benzyl (S)-2-((5-(2-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidine-2-carboxamido)quinolin-6-yl)pyrimidin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

benzyl (S)-2-((5-(2-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidine-2-carboxamido)quinolin-6-yl)pyrimidin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

benzyl (S)-2-((5-bromopyrimidin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

benzyl (S)-2-((5-bromopyrimidin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

benzyl (S)-2-((5-(2-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidine-2-carboxamido)quinolin-6-yl)pyrimidin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

benzyl (S)-2-((5-(2-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidine-2-carboxamido)quinolin-6-yl)pyrimidin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

benzyl (S)-2-(chlorocarbonyl)pyrrolidine-1-carboxylate

benzyl (S)-2-(chlorocarbonyl)pyrrolidine-1-carboxylate

benzyl (S)-2-((5-(2-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidine-2-carboxamido)quinolin-6-yl)pyrimidin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

benzyl (S)-2-((5-(2-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidine-2-carboxamido)quinolin-6-yl)pyrimidin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

1312611-23-6

benzyl (S)-2-((5-(2-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidine-2-carboxamido)quinolin-6-yl)pyrimidin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

benzyl (S)-2-((5-(2-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidine-2-carboxamido)quinolin-6-yl)pyrimidin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

上游原料

tert-butyl (S)-2-((6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinolin-2-yl)carbamoyl)pyrrolidine-1-carboxylate tert-butyl (S)-2-((6-bromoquinolin-2-yl)carbamoyl)pyrrolidine-1-carboxylate benzyl (S)-2-((5-bromopyrimidin-2-yl)carbamoyl)pyrrolidine-1-carboxylate

下游产品

methyl ((S)-3-methyl-1-oxo-1-((S)-2-((6-(2-((S)-1-(2-phenylacetyl)pyrrolidine-2-carboxamido)pyrimidin-5-yl)quinolin-2-yl)carbamoyl)pyrrolidin-1-yl)butan-2-yl)carbamate methyl ((S)-3-methyl-1-oxo-1-((S)-2-((6-(2-((S)-pyrrolidine-2-carboxamido)pyrimidin-5-yl)quinolin-2-yl)carbamoyl)pyrrolidin-1-yl)butan-2-yl)carbamate