百科

1-((1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-7-((tert-butyldimethylsilyl)oxy)-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-5-(thiazol-2-yl)pyrimidine-2,4(1H,3H)-dione

1-((1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-7-((tert-butyldimethylsilyl)oxy)-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-5-(thiazol-2-yl)pyrimidine-2,4(1H,3H)-dione

CAS号：1314716-27-2

英文名：1-((1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-7-((tert-butyldimethylsilyl)oxy)-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-5-(thiazol-2-yl)pyrimidine-2,4(1H,3H)-dione

分子式：C40H45N3O8SSi

分子量：755.951

上游原料

(3R,4S,5S)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-5-(((methylsulfonyl)oxy)methyl)-4-(naphthalen-2-ylmethoxy)tetrahydrofuran-2,3-diyl diacetate

(3R,4S,5S)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-5-(((methylsulfonyl)oxy)methyl)-4-(naphthalen-2-ylmethoxy)tetrahydrofuran-2,3-diyl diacetate

((1R,3R,4R,7S)-7-acetoxy-3-(5-iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-1-yl)methyl acetate

((1R,3R,4R,7S)-7-acetoxy-3-(5-iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-1-yl)methyl acetate

上游原料

(3R,4S,5S)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-5-(((methylsulfonyl)oxy)methyl)-4-(naphthalen-2-ylmethoxy)tetrahydrofuran-2,3-diyl diacetate ((1R,3R,4R,7S)-7-acetoxy-3-(5-iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-1-yl)methyl acetate

下游产品

(1R,3R,4R,7S)-3-(4-benzamido-2-oxo-5-(thiazol-2-yl)pyrimidin-1(2H)-yl)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite