百科

(3S,6E,8R,9S,12E,14R,15S)-8-hydroxy-14-(2-methoxyethoxy)methoxy-3,9,15-trimethyl-4-aza-10,16-dioxa-6,12-cyclohexadecadiene-1,5,11-trione

(3S,6E,8R,9S,12E,14R,15S)-8-hydroxy-14-(2-methoxyethoxy)methoxy-3,9,15-trimethyl-4-aza-10,16-dioxa-6,12-cyclohexadecadiene-1,5,11-trione

CAS号：1335286-52-6

英文名：(3S,6E,8R,9S,12E,14R,15S)-8-hydroxy-14-(2-methoxyethoxy)methoxy-3,9,15-trimethyl-4-aza-10,16-dioxa-6,12-cyclohexadecadiene-1,5,11-trione

分子式：C20H31NO9

分子量：429.461

合成路线

(4R,5S)-(E)-5-(t-butyl(dimethyl)silyloxy)-4-(β-methoxyethoxy)methoxy-2-hexenoic acid

(4R,5S)-(E)-5-(t-butyl(dimethyl)silyloxy)-4-(β-methoxyethoxy)methoxy-2-hexenoic acid

(3S,6E,8R,9S,12E,14R,15S)-8-hydroxy-14-(2-methoxyethoxy)methoxy-3,9,15-trimethyl-4-aza-10,16-dioxa-6,12-cyclohexadecadiene-1,5,11-trione

(3S,6E,8R,9S,12E,14R,15S)-8-hydroxy-14-(2-methoxyethoxy)methoxy-3,9,15-trimethyl-4-aza-10,16-dioxa-6,12-cyclohexadecadiene-1,5,11-trione

(1S,2R,3E)-4-[(1S,2R)-2-hydroxy-1-methyl-3-butenyloxy]-2-(methoxyethoxy)methoxy-1-methyl-3-butenyl (S)-3-acryloylamino-butenoate

(1S,2R,3E)-4-[(1S,2R)-2-hydroxy-1-methyl-3-butenyloxy]-2-(methoxyethoxy)methoxy-1-methyl-3-butenyl (S)-3-acryloylamino-butenoate

(3S,6E,8R,9S,12E,14R,15S)-8-hydroxy-14-(2-methoxyethoxy)methoxy-3,9,15-trimethyl-4-aza-10,16-dioxa-6,12-cyclohexadecadiene-1,5,11-trione

(3S,6E,8R,9S,12E,14R,15S)-8-hydroxy-14-(2-methoxyethoxy)methoxy-3,9,15-trimethyl-4-aza-10,16-dioxa-6,12-cyclohexadecadiene-1,5,11-trione

(1S,2R)-2-tert-butyldiphenylsilyloxy-1-methyl-3-butenyl (2E,4R,5S)-5-tert-butyldimethylsilyloxy-4-(2-methoxyethoxy)methoxy-2-hexenoate

(1S,2R)-2-tert-butyldiphenylsilyloxy-1-methyl-3-butenyl (2E,4R,5S)-5-tert-butyldimethylsilyloxy-4-(2-methoxyethoxy)methoxy-2-hexenoate

(3S,6E,8R,9S,12E,14R,15S)-8-hydroxy-14-(2-methoxyethoxy)methoxy-3,9,15-trimethyl-4-aza-10,16-dioxa-6,12-cyclohexadecadiene-1,5,11-trione

(3S,6E,8R,9S,12E,14R,15S)-8-hydroxy-14-(2-methoxyethoxy)methoxy-3,9,15-trimethyl-4-aza-10,16-dioxa-6,12-cyclohexadecadiene-1,5,11-trione

(1S,2R,3E)-4-[(1S,2R)-2-tert-butyldiphenylsilyloxy-1-methyl-3-butenyloxy]-2-(methoxyethoxy)methoxy-1-methyl-3-butenyl (S)-3-tert-butoxycarbonylamino-butenoate

(1S,2R,3E)-4-[(1S,2R)-2-tert-butyldiphenylsilyloxy-1-methyl-3-butenyloxy]-2-(methoxyethoxy)methoxy-1-methyl-3-butenyl (S)-3-tert-butoxycarbonylamino-butenoate

(3S,6E,8R,9S,12E,14R,15S)-8-hydroxy-14-(2-methoxyethoxy)methoxy-3,9,15-trimethyl-4-aza-10,16-dioxa-6,12-cyclohexadecadiene-1,5,11-trione

(3S,6E,8R,9S,12E,14R,15S)-8-hydroxy-14-(2-methoxyethoxy)methoxy-3,9,15-trimethyl-4-aza-10,16-dioxa-6,12-cyclohexadecadiene-1,5,11-trione

5-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-hex-2-enoic acid ethyl ester

5-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-hex-2-enoic acid ethyl ester

(3S,6E,8R,9S,12E,14R,15S)-8-hydroxy-14-(2-methoxyethoxy)methoxy-3,9,15-trimethyl-4-aza-10,16-dioxa-6,12-cyclohexadecadiene-1,5,11-trione

(3S,6E,8R,9S,12E,14R,15S)-8-hydroxy-14-(2-methoxyethoxy)methoxy-3,9,15-trimethyl-4-aza-10,16-dioxa-6,12-cyclohexadecadiene-1,5,11-trione

上游原料

(1S,2R,3E)-4-[(1S,2R)-2-tert-butyldiphenylsilyloxy-1-methyl-3-butenyloxy]-2-(methoxyethoxy)methoxy-1-methyl-3-butenyl (S)-3-tert-butoxycarbonylamino-butenoate (1S,2R,3E)-4-[(1S,2R)-2-hydroxy-1-methyl-3-butenyloxy]-2-(methoxyethoxy)methoxy-1-methyl-3-butenyl (S)-3-acryloylamino-butenoate 5-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-hex-2-enoic acid ethyl ester (1S,2R)-2-tert-butyldiphenylsilyloxy-1-methyl-3-butenyl (2E,4R,5S)-5-tert-butyldimethylsilyloxy-4-(2-methoxyethoxy)methoxy-2-hexenoate (4R,5S)-(E)-5-(t-butyl(dimethyl)silyloxy)-4-(β-methoxyethoxy)methoxy-2-hexenoic acid

下游产品

(4S,7E,9R,10S,13E,15R,16S)-9,15-dihydroxy-4,10,16-trimethyl-1,11-dioxa-5-azacyclohexadeca-7,13-diene-2,6,12-trione