百科

7-hydroxy-2-((2S,5S)-5-methylpiperidin-2-yl)pyrazolo[1,5-a]pyrimidin-5(4H)-one

7-hydroxy-2-((2S,5S)-5-methylpiperidin-2-yl)pyrazolo[1,5-a]pyrimidin-5(4H)-one

CAS号：1353629-18-1

英文名：7-hydroxy-2-((2S,5S)-5-methylpiperidin-2-yl)pyrazolo[1,5-a]pyrimidin-5(4H)-one

分子式：C12H16N4O2

分子量：248.281

合成路线

(25,5S)-1-benzyl 2-methyl 5-methylpiperidine-1,2-dicarboxylate

(25,5S)-1-benzyl 2-methyl 5-methylpiperidine-1,2-dicarboxylate

7-hydroxy-2-((2S,5S)-5-methylpiperidin-2-yl)pyrazolo[1,5-a]pyrimidin-5(4H)-one

7-hydroxy-2-((2S,5S)-5-methylpiperidin-2-yl)pyrazolo[1,5-a]pyrimidin-5(4H)-one

benzyl (2S,5S)-2-(7-hydroxy-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carboxylate

benzyl (2S,5S)-2-(7-hydroxy-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carboxylate

7-hydroxy-2-((2S,5S)-5-methylpiperidin-2-yl)pyrazolo[1,5-a]pyrimidin-5(4H)-one

7-hydroxy-2-((2S,5S)-5-methylpiperidin-2-yl)pyrazolo[1,5-a]pyrimidin-5(4H)-one

benzyl (2S,5S)-2-(5-amino-1H-pyrazol-3-yl)-5-methylpiperidine-1-carboxylate

benzyl (2S,5S)-2-(5-amino-1H-pyrazol-3-yl)-5-methylpiperidine-1-carboxylate

7-hydroxy-2-((2S,5S)-5-methylpiperidin-2-yl)pyrazolo[1,5-a]pyrimidin-5(4H)-one

7-hydroxy-2-((2S,5S)-5-methylpiperidin-2-yl)pyrazolo[1,5-a]pyrimidin-5(4H)-one

上游原料

(25,5S)-1-benzyl 2-methyl 5-methylpiperidine-1,2-dicarboxylate benzyl (2S,5S)-2-(7-hydroxy-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carboxylate benzyl (2S,5S)-2-(5-amino-1H-pyrazol-3-yl)-5-methylpiperidine-1-carboxylate

下游产品

N-(2-((2S,5S)-2-(5-(3-aminoazetidin-1-yl)-7-morpholinopyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide hydrochloride N-(4-chloro-2-((2S,5S)-2-(5,7-dichloropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carbonyl)phenyl)methanesulfonamide N-(4-chloro-2-((2S,5S)-2-(5-chloro-7-morpholinopyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carbonyl)phenyl)methanesulfonamide 5,7-dichloro-2-((2S,5S)-5-methylpiperidin-2-yl)pyrazolo[1,5-a]pyrimidine