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N-(4-chloro-2-((2S,5S)-2-(5,7-dichloropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carbonyl)phenyl)methanesulfonamide

N-(4-chloro-2-((2S,5S)-2-(5,7-dichloropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carbonyl)phenyl)methanesulfonamide

CAS号：1353629-20-5

英文名：N-(4-chloro-2-((2S,5S)-2-(5,7-dichloropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carbonyl)phenyl)methanesulfonamide

分子式：C20H20Cl3N5O3S

分子量：516.828

合成路线

5-chloro-2-(methylsulfonamido)benzoyl chloride

5-chloro-2-(methylsulfonamido)benzoyl chloride

5,7-dichloro-2-((2S,5S)-5-methylpiperidin-2-yl)pyrazolo[1,5-a]pyrimidine

5,7-dichloro-2-((2S,5S)-5-methylpiperidin-2-yl)pyrazolo[1,5-a]pyrimidine

N-(4-chloro-2-((2S,5S)-2-(5,7-dichloropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carbonyl)phenyl)methanesulfonamide

N-(4-chloro-2-((2S,5S)-2-(5,7-dichloropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carbonyl)phenyl)methanesulfonamide

(25,5S)-1-benzyl 2-methyl 5-methylpiperidine-1,2-dicarboxylate

(25,5S)-1-benzyl 2-methyl 5-methylpiperidine-1,2-dicarboxylate

N-(4-chloro-2-((2S,5S)-2-(5,7-dichloropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carbonyl)phenyl)methanesulfonamide

N-(4-chloro-2-((2S,5S)-2-(5,7-dichloropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carbonyl)phenyl)methanesulfonamide

benzyl (2S,5S)-2-(5-amino-1H-pyrazol-3-yl)-5-methylpiperidine-1-carboxylate

benzyl (2S,5S)-2-(5-amino-1H-pyrazol-3-yl)-5-methylpiperidine-1-carboxylate

N-(4-chloro-2-((2S,5S)-2-(5,7-dichloropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carbonyl)phenyl)methanesulfonamide

N-(4-chloro-2-((2S,5S)-2-(5,7-dichloropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carbonyl)phenyl)methanesulfonamide

benzyl (2S,5S)-2-(7-hydroxy-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carboxylate

benzyl (2S,5S)-2-(7-hydroxy-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carboxylate

N-(4-chloro-2-((2S,5S)-2-(5,7-dichloropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carbonyl)phenyl)methanesulfonamide

N-(4-chloro-2-((2S,5S)-2-(5,7-dichloropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carbonyl)phenyl)methanesulfonamide

7-hydroxy-2-((2S,5S)-5-methylpiperidin-2-yl)pyrazolo[1,5-a]pyrimidin-5(4H)-one

7-hydroxy-2-((2S,5S)-5-methylpiperidin-2-yl)pyrazolo[1,5-a]pyrimidin-5(4H)-one

N-(4-chloro-2-((2S,5S)-2-(5,7-dichloropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carbonyl)phenyl)methanesulfonamide

N-(4-chloro-2-((2S,5S)-2-(5,7-dichloropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carbonyl)phenyl)methanesulfonamide

上游原料

5-chloro-2-(methylsulfonamido)benzoyl chloride 7-hydroxy-2-((2S,5S)-5-methylpiperidin-2-yl)pyrazolo[1,5-a]pyrimidin-5(4H)-one (25,5S)-1-benzyl 2-methyl 5-methylpiperidine-1,2-dicarboxylate benzyl (2S,5S)-2-(5-amino-1H-pyrazol-3-yl)-5-methylpiperidine-1-carboxylate benzyl (2S,5S)-2-(7-hydroxy-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carboxylate 5,7-dichloro-2-((2S,5S)-5-methylpiperidin-2-yl)pyrazolo[1,5-a]pyrimidine

下游产品

N-(2-((2S,5S)-2-(5-(3-aminoazetidin-1-yl)-7-morpholinopyrazolo[1,5-a]pyrimidin-2-yl)-5-methylpiperidine-1-carbonyl)-4-chlorophenyl)methanesulfonamide hydrochloride