百科

N-(4-(5-amino-2-(3-methyl-1H-1,2,4-triazol-1-yl)phenoxy)butyl)-2-chloro-8-(4-fluorophenyl)-6-methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-amine

N-(4-(5-amino-2-(3-methyl-1H-1,2,4-triazol-1-yl)phenoxy)butyl)-2-chloro-8-(4-fluorophenyl)-6-methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-amine

CAS号：1356010-63-3

英文名：N-(4-(5-amino-2-(3-methyl-1H-1,2,4-triazol-1-yl)phenoxy)butyl)-2-chloro-8-(4-fluorophenyl)-6-methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-amine

分子式：C27H30ClFN8O

分子量：537.032

合成路线

ethyl α-(4-fluorophenyl)-α-cyanoacetate

ethyl α-(4-fluorophenyl)-α-cyanoacetate

N-(4-(5-amino-2-(3-methyl-1H-1,2,4-triazol-1-yl)phenoxy)butyl)-2-chloro-8-(4-fluorophenyl)-6-methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-amine

N-(4-(5-amino-2-(3-methyl-1H-1,2,4-triazol-1-yl)phenoxy)butyl)-2-chloro-8-(4-fluorophenyl)-6-methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-amine

ethyl 3-((3-ethoxy-3-oxopropyl)(methyl)amino)-2-(4-fluorophenyl)propanoate

ethyl 3-((3-ethoxy-3-oxopropyl)(methyl)amino)-2-(4-fluorophenyl)propanoate

N-(4-(5-amino-2-(3-methyl-1H-1,2,4-triazol-1-yl)phenoxy)butyl)-2-chloro-8-(4-fluorophenyl)-6-methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-amine

N-(4-(5-amino-2-(3-methyl-1H-1,2,4-triazol-1-yl)phenoxy)butyl)-2-chloro-8-(4-fluorophenyl)-6-methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-amine

上游原料

ethyl α-(4-fluorophenyl)-α-cyanoacetate

下游产品

(+/-)-19-(4-fluorophenyl)-17-methyl-7-(3-methyl-1H-1,2,4-triazol-1-yl)-11,12,13,14,16,17,18,19-octahydro-10H-15,2-(azeno)-8,4-(metheno)pyrido[3,4-h][1,6,10,12]oxatriazacycloheptadecine trifluoroacetate