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(3aS,4R,6aR)-N-((R)-3-(3-bromophenoxy)-2-(((tert-butyldimethylsilyl)oxy)methyl)propyl)-5-(2-methoxyacetyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyrrole-4-carboxamide

CAS号：1357622-61-7

英文名：(3aS,4R,6aR)-N-((R)-3-(3-bromophenoxy)-2-(((tert-butyldimethylsilyl)oxy)methyl)propyl)-5-(2-methoxyacetyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyrrole-4-carboxamide

分子式：C27H43BrN2O7Si

分子量：615.629

合成路线

873550-74-4

(2S,3R)-4-azido-2,3-O-isopropylidene-1,2,3-butanetriol

1357622-61-7

(3aS,4R,6aR)-N-((R)-3-(3-bromophenoxy)-2-(((tert-butyldimethylsilyl)oxy)methyl)propyl)-5-(2-methoxyacetyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyrrole-4-carboxamide

873550-75-5

(2R,3R)-4-azido-2,3-O-isopropylidene-2,3-dihydroxybutanal

1357622-61-7

(3aS,4R,6aR)-N-((R)-3-(3-bromophenoxy)-2-(((tert-butyldimethylsilyl)oxy)methyl)propyl)-5-(2-methoxyacetyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyrrole-4-carboxamide

1357622-26-4

(R,E)-2-(3-bromophenoxy)methyl-5-methylhex-3-enyl acetate

1357622-61-7

(3aS,4R,6aR)-N-((R)-3-(3-bromophenoxy)-2-(((tert-butyldimethylsilyl)oxy)methyl)propyl)-5-(2-methoxyacetyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyrrole-4-carboxamide

1357622-27-5

(R)-3-acetoxy-2-((3-bromophenoxy)methyl)propanol

1357622-61-7

(3aS,4R,6aR)-N-((R)-3-(3-bromophenoxy)-2-(((tert-butyldimethylsilyl)oxy)methyl)propyl)-5-(2-methoxyacetyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyrrole-4-carboxamide

1357622-28-6

(R)-1-acetoxy-3-azido-2-((3-bromophenoxy)methyl)propane

1357622-61-7

(3aS,4R,6aR)-N-((R)-3-(3-bromophenoxy)-2-(((tert-butyldimethylsilyl)oxy)methyl)propyl)-5-(2-methoxyacetyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyrrole-4-carboxamide

1357622-29-7

(S)-3-azido-2-((3-bromophenoxy)methyl)propanol

1357622-61-7

(3aS,4R,6aR)-N-((R)-3-(3-bromophenoxy)-2-(((tert-butyldimethylsilyl)oxy)methyl)propyl)-5-(2-methoxyacetyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyrrole-4-carboxamide

1357622-30-0

(R)-1-azido-3-(tert-butyl)dimethylsilyloxy-2-((3-bromophenoxy)methyl)propane

1357622-61-7

(3aS,4R,6aR)-N-((R)-3-(3-bromophenoxy)-2-(((tert-butyldimethylsilyl)oxy)methyl)propyl)-5-(2-methoxyacetyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyrrole-4-carboxamide

1357622-34-4

(R)-1-amino-3-(tert-butyl)dimethylsilyloxy-2-((3-bromophenoxy)methyl)propane

1357622-61-7

(3aS,4R,6aR)-N-((R)-3-(3-bromophenoxy)-2-(((tert-butyldimethylsilyl)oxy)methyl)propyl)-5-(2-methoxyacetyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyrrole-4-carboxamide

1357622-54-8

((4S,5R)-5-(azidomethyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl butanoate

1357622-61-7

(3aS,4R,6aR)-N-((R)-3-(3-bromophenoxy)-2-(((tert-butyldimethylsilyl)oxy)methyl)propyl)-5-(2-methoxyacetyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyrrole-4-carboxamide

1357623-20-1

(R)-3-(3-bromophenoxy)-2-(((methylsulfonyl)oxy)methyl)propyl acetate

1357622-61-7

(3aS,4R,6aR)-N-((R)-3-(3-bromophenoxy)-2-(((tert-butyldimethylsilyl)oxy)methyl)propyl)-5-(2-methoxyacetyl)-2,2-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyrrole-4-carboxamide

上游原料

(2S,3R)-4-azido-2,3-O-isopropylidene-1,2,3-butanetriol (R)-1-amino-3-(tert-butyl)dimethylsilyloxy-2-((3-bromophenoxy)methyl)propane ((4S,5R)-5-(azidomethyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl butanoate (2R,3R)-4-azido-2,3-O-isopropylidene-2,3-dihydroxybutanal (R)-1-(tert-butyl)dimethylsilyloxy-2-((3-bromophenoxy)methyl)-3-formylaminopropane (R)-3-(3-bromophenoxy)-2-(((methylsulfonyl)oxy)methyl)propyl acetate (R,E)-2-(3-bromophenoxy)methyl-5-methylhex-3-enyl acetate (R)-1-azido-3-(tert-butyl)dimethylsilyloxy-2-((3-bromophenoxy)methyl)propane (R)-1-acetoxy-3-azido-2-((3-bromophenoxy)methyl)propane (R)-3-acetoxy-2-((3-bromophenoxy)methyl)propanol (S)-3-azido-2-((3-bromophenoxy)methyl)propanol ((4S,5R)-5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl butanoate

下游产品

(2R,3S,4R)-N-((S)-3-(3-bromophenoxy)-2-(hydroxymethyl)propyl)-3,4-dihydroxy-1-(2-methoxyacetyl)pyrrolidine-2-carboxamide