百科

(S)-methyl 2-((2R,3S,Z)-1-((S)-2-benzamido-6-((Z)-2,3-bis(tert-butoxycarbonyl)guanidino)hexanoyl)-4-ethylidene-3-methylpyrrolidine-2-carboxamido)-4-methylpentanoate

CAS号：1360186-75-9

英文名：(S)-methyl 2-((2R,3S,Z)-1-((S)-2-benzamido-6-((Z)-2,3-bis(tert-butoxycarbonyl)guanidino)hexanoyl)-4-ethylidene-3-methylpyrrolidine-2-carboxamido)-4-methylpentanoate

分子式：C39H60N6O9

分子量：756.928

合成路线

308850-43-3

methyl (Z)-N6-(N,N'-bis(tert-butoxycarbonyl)carbamimidoyl)-L-lysinate

1360186-75-9

(S)-methyl 2-((2R,3S,Z)-1-((S)-2-benzamido-6-((Z)-2,3-bis(tert-butoxycarbonyl)guanidino)hexanoyl)-4-ethylidene-3-methylpyrrolidine-2-carboxamido)-4-methylpentanoate

1360186-31-7

(R)-tert-butyl but-2-ynyl(1-hydroxybut-3-en-2-yl)carbamate

1360186-75-9

(S)-methyl 2-((2R,3S,Z)-1-((S)-2-benzamido-6-((Z)-2,3-bis(tert-butoxycarbonyl)guanidino)hexanoyl)-4-ethylidene-3-methylpyrrolidine-2-carboxamido)-4-methylpentanoate

1360186-37-3

(7S,7aR,Z)-6-ethylidene-7-methyltetrahydropyrrolo[1,2-c]oxazol-3(1H)-one

1360186-75-9

(S)-methyl 2-((2R,3S,Z)-1-((S)-2-benzamido-6-((Z)-2,3-bis(tert-butoxycarbonyl)guanidino)hexanoyl)-4-ethylidene-3-methylpyrrolidine-2-carboxamido)-4-methylpentanoate

1360186-47-5

(2R,3S,Z)-tert-butyl 4-ethylidene-2-(hydroxymethyl)-3-methylpyrrolidine-1-carboxylate

1360186-75-9

(S)-methyl 2-((2R,3S,Z)-1-((S)-2-benzamido-6-((Z)-2,3-bis(tert-butoxycarbonyl)guanidino)hexanoyl)-4-ethylidene-3-methylpyrrolidine-2-carboxamido)-4-methylpentanoate

1360186-56-6

(2R,3S,Z)-1-(tert-butoxycarbonyl)-4-ethylidene-3-methylpyrrolidine-2-carboxylic acid

1360186-75-9

(S)-methyl 2-((2R,3S,Z)-1-((S)-2-benzamido-6-((Z)-2,3-bis(tert-butoxycarbonyl)guanidino)hexanoyl)-4-ethylidene-3-methylpyrrolidine-2-carboxamido)-4-methylpentanoate

1360186-66-8

(2R,3S,Z)-tert-butyl 4-ethylidene-2-((S)-1-methoxy-4-methyl-1-oxopentan-2-ylcarbamoyl)-3-methylpyrrolidine-1-carboxylate

1360186-75-9

(S)-methyl 2-((2R,3S,Z)-1-((S)-2-benzamido-6-((Z)-2,3-bis(tert-butoxycarbonyl)guanidino)hexanoyl)-4-ethylidene-3-methylpyrrolidine-2-carboxamido)-4-methylpentanoate

130336-19-5

DL-Lysine, methyl ester, monohydrochloride

1360186-75-9

(S)-methyl 2-((2R,3S,Z)-1-((S)-2-benzamido-6-((Z)-2,3-bis(tert-butoxycarbonyl)guanidino)hexanoyl)-4-ethylidene-3-methylpyrrolidine-2-carboxamido)-4-methylpentanoate

1143572-00-2

1360186-75-9

(S)-methyl 2-((2R,3S,Z)-1-((S)-2-benzamido-6-((Z)-2,3-bis(tert-butoxycarbonyl)guanidino)hexanoyl)-4-ethylidene-3-methylpyrrolidine-2-carboxamido)-4-methylpentanoate

上游原料

(R)-tert-butyl but-2-ynyl(1-hydroxybut-3-en-2-yl)carbamate (2R,3S,Z)-tert-butyl 4-ethylidene-2-(hydroxymethyl)-3-methylpyrrolidine-1-carboxylate (7S,7aR,Z)-6-ethylidene-7-methyltetrahydropyrrolo[1,2-c]oxazol-3(1H)-one (2R,3S,Z)-1-(tert-butoxycarbonyl)-4-ethylidene-3-methylpyrrolidine-2-carboxylic acid (2R,3S,Z)-tert-butyl 4-ethylidene-2-((S)-1-methoxy-4-methyl-1-oxopentan-2-ylcarbamoyl)-3-methylpyrrolidine-1-carboxylate methyl (Z)-N6-(N,N'-bis(tert-butoxycarbonyl)carbamimidoyl)-L-lysinate

下游产品

(S)-2-{(2R,3S,Z)-1-[(S)-2-benzamido-6-guanidinohexanoyl]-4-ethylidene-3-methylpyrrolidine-2-carboxamido}-4-methyl-pentanoic acid