百科

methyl 2-((2R,4a'R,5R,8a'R)-2'-(bromomethyl)-5,5',5',8a'-tetramethyl-4,4a',5,5',6',7',8',8a'-octahydro-3H,4'H-spiro[furan-2,1'-naphthalen]-5-yl)acetate

methyl 2-((2R,4a'R,5R,8a'R)-2'-(bromomethyl)-5,5',5',8a'-tetramethyl-4,4a',5,5',6',7',8',8a'-octahydro-3H,4'H-spiro[furan-2,1'-naphthalen]-5-yl)acetate

CAS号：137208-07-2

英文名：methyl 2-((2R,4a'R,5R,8a'R)-2'-(bromomethyl)-5,5',5',8a'-tetramethyl-4,4a',5,5',6',7',8',8a'-octahydro-3H,4'H-spiro[furan-2,1'-naphthalen]-5-yl)acetate

分子式：C21H33BrO3

分子量：413.389

合成路线

methyl (2S,4'aR,5R,8'aR)-4,4'a,5,5',6',7',8',8'a-octahydro-2',5,5',5',8'a-pentamethylspiro<furan-2(3H),1'(4'H)-naphthalene>-5-acetate

methyl (2S,4'aR,5R,8'aR)-4,4'a,5,5',6',7',8',8'a-octahydro-2',5,5',5',8'a-pentamethylspiro<furan-2(3H),1'(4'H)-naphthalene>-5-acetate

methyl 2-((2R,3'S,4a'R,5R,8a'R)-3'-bromo-5,5',5',8a'-tetramethyl-2'-methylenedecahydro-2'H,3H-spiro[furan-2,1'-naphthalen]-5-yl)acetate

methyl 2-((2R,3'S,4a'R,5R,8a'R)-3'-bromo-5,5',5',8a'-tetramethyl-2'-methylenedecahydro-2'H,3H-spiro[furan-2,1'-naphthalen]-5-yl)acetate

methyl 2-((2R,4a'R,5R,8a'R)-2'-(bromomethyl)-5,5',5',8a'-tetramethyl-4,4a',5,5',6',7',8',8a'-octahydro-3H,4'H-spiro[furan-2,1'-naphthalen]-5-yl)acetate

methyl 2-((2R,4a'R,5R,8a'R)-2'-(bromomethyl)-5,5',5',8a'-tetramethyl-4,4a',5,5',6',7',8',8a'-octahydro-3H,4'H-spiro[furan-2,1'-naphthalen]-5-yl)acetate

(+)-grindelic acid

(+)-grindelic acid

methyl 2-((2R,4a'R,5R,8a'R)-2'-(bromomethyl)-5,5',5',8a'-tetramethyl-4,4a',5,5',6',7',8',8a'-octahydro-3H,4'H-spiro[furan-2,1'-naphthalen]-5-yl)acetate

methyl 2-((2R,4a'R,5R,8a'R)-2'-(bromomethyl)-5,5',5',8a'-tetramethyl-4,4a',5,5',6',7',8',8a'-octahydro-3H,4'H-spiro[furan-2,1'-naphthalen]-5-yl)acetate

上游原料

(+)-grindelic acid methyl (2S,4'aR,5R,8'aR)-4,4'a,5,5',6',7',8',8'a-octahydro-2',5,5',5',8'a-pentamethylspiro<furan-2(3H),1'(4'H)-naphthalene>-5-acetate

下游产品

17-acetoxy-grindelane methyl ester methyl 2-((2R,3'S,4a'R,5R,8a'R)-3'-bromo-5,5',5',8a'-tetramethyl-2'-methylenedecahydro-2'H,3H-spiro[furan-2,1'-naphthalen]-5-yl)acetate