百科

(2R,3R,4R,5R)-2-((2S,5S)-2-(aminomethyl)-6-methoxy-6-oxo-5-(2,2,2-trifluoroacetamido)hexyl)-5-(6-benzamido-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate

(2R,3R,4R,5R)-2-((2S,5S)-2-(aminomethyl)-6-methoxy-6-oxo-5-(2,2,2-trifluoroacetamido)hexyl)-5-(6-benzamido-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate

CAS号：1431135-23-7

英文名：(2R,3R,4R,5R)-2-((2S,5S)-2-(aminomethyl)-6-methoxy-6-oxo-5-(2,2,2-trifluoroacetamido)hexyl)-5-(6-benzamido-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate

分子式：C30H34F3N7O9

分子量：693.628

合成路线

(2R,3R,4R,5R)-2-(6-benzamido-9H-purin-9-yl)-5-((2S,5S)-2-((benzyl((benzyloxy)carbonyl)amino)methyl)-6-methoxy-6-oxo-5-(2,2,2-trifluoroacetamido)hexyl)tetrahydrofuran-3,4-diyl diacetate

(2R,3R,4R,5R)-2-(6-benzamido-9H-purin-9-yl)-5-((2S,5S)-2-((benzyl((benzyloxy)carbonyl)amino)methyl)-6-methoxy-6-oxo-5-(2,2,2-trifluoroacetamido)hexyl)tetrahydrofuran-3,4-diyl diacetate

(2R,3R,4R,5R)-2-((2S,5S)-2-(aminomethyl)-6-methoxy-6-oxo-5-(2,2,2-trifluoroacetamido)hexyl)-5-(6-benzamido-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate

(2R,3R,4R,5R)-2-((2S,5S)-2-(aminomethyl)-6-methoxy-6-oxo-5-(2,2,2-trifluoroacetamido)hexyl)-5-(6-benzamido-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate

上游原料

(2R,3R,4R,5R)-2-(6-benzamido-9H-purin-9-yl)-5-((2S,5S)-2-((benzyl((benzyloxy)carbonyl)amino)methyl)-6-methoxy-6-oxo-5-(2,2,2-trifluoroacetamido)hexyl)tetrahydrofuran-3,4-diyl diacetate

下游产品

(2R,3R,4R,5R)-2-(6-benzamido-9H-purin-9-yl)-5-((2S,5S)-2-((2,3-bis(tert-butoxycarbonyl)guanidino)methyl)-6-methoxy-6-oxo-5-(2,2,2-trifluoroacetamido)hexyl)tetrahydrofuran-3,4-diyl diacetate (2S,5S)-2-amino-6-((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)-5-(guanidinomethyl)hexanoic acid