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N-(2-fluoro-3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((tetrahydrofuran-3-yl)methyl)pyrido[2,3-b]pyrazin-6-amine

N-(2-fluoro-3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((tetrahydrofuran-3-yl)methyl)pyrido[2,3-b]pyrazin-6-amine

CAS号：1431871-85-0

英文名：N-(2-fluoro-3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((tetrahydrofuran-3-yl)methyl)pyrido[2,3-b]pyrazin-6-amine

分子式：C24H25FN6O3

分子量：464.492

合成路线

3-(1-methyl-1H-pyrazol-4-yl)pyrido[2,3-b]pyrazin-6(5H)-one

3-(1-methyl-1H-pyrazol-4-yl)pyrido[2,3-b]pyrazin-6(5H)-one

N-(2-fluoro-3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((tetrahydrofuran-3-yl)methyl)pyrido[2,3-b]pyrazin-6-amine

N-(2-fluoro-3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((tetrahydrofuran-3-yl)methyl)pyrido[2,3-b]pyrazin-6-amine

6-chloro-3-(1-methyl-1H-pyrazol-4-yl)pyrido[2,3-b]pyrazine

6-chloro-3-(1-methyl-1H-pyrazol-4-yl)pyrido[2,3-b]pyrazine

N-(2-fluoro-3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((tetrahydrofuran-3-yl)methyl)pyrido[2,3-b]pyrazin-6-amine

N-(2-fluoro-3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((tetrahydrofuran-3-yl)methyl)pyrido[2,3-b]pyrazin-6-amine

3-bromo-6-chloropyrido[2,3-b]pyrazine

3-bromo-6-chloropyrido[2,3-b]pyrazine

N-(2-fluoro-3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((tetrahydrofuran-3-yl)methyl)pyrido[2,3-b]pyrazin-6-amine

N-(2-fluoro-3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((tetrahydrofuran-3-yl)methyl)pyrido[2,3-b]pyrazin-6-amine

3,6-dichloropyrido[2,3-b]pyrazine

3,6-dichloropyrido[2,3-b]pyrazine

N-(2-fluoro-3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((tetrahydrofuran-3-yl)methyl)pyrido[2,3-b]pyrazin-6-amine

N-(2-fluoro-3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((tetrahydrofuran-3-yl)methyl)pyrido[2,3-b]pyrazin-6-amine

上游原料

3-bromo-6-chloropyrido[2,3-b]pyrazine 3,6-dichloropyrido[2,3-b]pyrazine 6-chloro-3-(1-methyl-1H-pyrazol-4-yl)pyrido[2,3-b]pyrazine 3-(1-methyl-1H-pyrazol-4-yl)pyrido[2,3-b]pyrazin-6(5H)-one

下游产品

(R)-N-(2-fluoro-3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((tetrahydrofuran-3-yl)methyl)pyrido[2,3-b]pyrazin-6-amine (S)-N-(2-fluoro-3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-((tetrahydrofuran-3-yl)methyl)pyrido[2,3-b]pyrazin-6-amine