百科

恩曲他滨

恩曲他滨

CAS号：143491-57-0

英文名：Emtricitabine

分子式：C8H10FN3O3S

分子量：247.247

合成路线

2',3'-dideoxy-5-fluoro-3'-thiacytidine hydrochloride

2',3'-dideoxy-5-fluoro-3'-thiacytidine hydrochloride

恩曲他滨

(2R,5S)-5-(4-氨基-5-氟-2-氧代-1(2H)-嘧啶基)-1,3-噁噻烷-2-羧酸 (1R,2S,5R)-5-甲基-2-(1-甲基乙基)环己酯

(2R,5S)-5-(4-氨基-5-氟-2-氧代-1(2H)-嘧啶基)-1,3-噁噻烷-2-羧酸 (1R,2S,5R)-5-甲基-2-(1-甲基乙基)环己酯

恩曲他滨

1313482-37-9

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4-amino-5-fluoro-1-((2R,5S)-2-hydroxymethyl-[1,3]oxathiolane-5-yl)-1H-pyrimidin-2-one 2-fluorobenzoic acid salt

4-amino-5-fluoro-1-((2R,5S)-2-hydroxymethyl-[1,3]oxathiolane-5-yl)-1H-pyrimidin-2-one 2-fluorobenzoic acid salt

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(-)-(2R,5S)-5-fluoro-1-[2-[[(tert-butyldiphenylsilyl)oxy]methyl]-1,3-oxathiolan-5-yl]-N4-benzoylcytosine

(-)-(2R,5S)-5-fluoro-1-[2-[[(tert-butyldiphenylsilyl)oxy]methyl]-1,3-oxathiolan-5-yl]-N4-benzoylcytosine

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5-(4-acetylamino-5-fluoro-2-oxo-2H-pyrimidin-1-yl)-[1,3]oxathiolane-2-carboxylic acid 2-isopropyl-5-methyl-cyclohexyl ester

5-(4-acetylamino-5-fluoro-2-oxo-2H-pyrimidin-1-yl)-[1,3]oxathiolane-2-carboxylic acid 2-isopropyl-5-methyl-cyclohexyl ester

恩曲他滨

上游原料

(2R,5S)-5-(4-氨基-5-氟-2-氧代-1(2H)-嘧啶基)-1,3-噁噻烷-2-羧酸 (1R,2S,5R)-5-甲基-2-(1-甲基乙基)环己酯 (-)-(2R,5S)-5-fluoro-1-[2-[[(tert-butyldiphenylsilyl)oxy]methyl]-1,3-oxathiolan-5-yl]-N4-benzoylcytosine 2',3'-dideoxy-5-fluoro-3'-thiacytidine hydrochloride 5-(4-acetylamino-5-fluoro-2-oxo-2H-pyrimidin-1-yl)-[1,3]oxathiolane-2-carboxylic acid 2-isopropyl-5-methyl-cyclohexyl ester 4-amino-5-fluoro-1-((2R,5S)-2-hydroxymethyl-[1,3]oxathiolane-5-yl)-1H-pyrimidin-2-one 2-fluorobenzoic acid salt

下游产品

4-氨基-1-((2R,5S)-2-((叔-丁基二甲基硅烷基氧基)甲基)-1,3-氧硫杂环戊烷-5-基)-5-氟嘧啶-2(1H)-酮