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(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

CAS号：1439381-92-6

英文名：(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

分子式：C23H46O5SSi2

分子量：490.844

合成路线

4,6-O-benzylidene-3-deoxy-2-O-(tert-butyldimethylsilyl)-3-C-ethenyl-α-D-altropyranoside

4,6-O-benzylidene-3-deoxy-2-O-(tert-butyldimethylsilyl)-3-C-ethenyl-α-D-altropyranoside

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

4,6-O-benzylidene-2-O-(tert-butyldimethylsilyl)-3-deoxy-3-C-(2-pivaloyloxyethyl)-α-D-altropyranoside

4,6-O-benzylidene-2-O-(tert-butyldimethylsilyl)-3-deoxy-3-C-(2-pivaloyloxyethyl)-α-D-altropyranoside

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

methyl 4-O-benzoyl-6-bromo-2-O-(tert-butyldimethylsilyl)-3,6-dideoxy-3-C-(2-pivaloyloxyethyl)-α-D-altropyranoside

methyl 4-O-benzoyl-6-bromo-2-O-(tert-butyldimethylsilyl)-3,6-dideoxy-3-C-(2-pivaloyloxyethyl)-α-D-altropyranoside

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

(3R,4R,5S)-3-benzoyloxy-5-[(tert-butyldimethylsilyl)oxy]-4-[(2-pivaloyloxy)ethyl]-6-(tosyloxy)hex-1-ene

(3R,4R,5S)-3-benzoyloxy-5-[(tert-butyldimethylsilyl)oxy]-4-[(2-pivaloyloxy)ethyl]-6-(tosyloxy)hex-1-ene

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

(2S,3R,4R)-4-benzoyloxy-2-(tert-butyldimethylsilyl)oxy-3-(2-pivaloyloxyethyl)hex-5-en-1-ol

(2S,3R,4R)-4-benzoyloxy-2-(tert-butyldimethylsilyl)oxy-3-(2-pivaloyloxyethyl)hex-5-en-1-ol

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(pivaloyloxy)ethyl]oct-1-en-7-yne

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(pivaloyloxy)ethyl]oct-1-en-7-yne

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

(3R,4R,5S)-3-benzoyloxy-5,6-epoxy-4-[(2-pivaloyloxy)ethyl]hex-1,5-diene

(3R,4R,5S)-3-benzoyloxy-5,6-epoxy-4-[(2-pivaloyloxy)ethyl]hex-1,5-diene

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

(4R,5S,6R)-6-benzoyloxy-5-[2-(pivaloyloxy)ethyl]-1-(trimethylsilyl)oct-7-en-1-yn-4-ol

(4R,5S,6R)-6-benzoyloxy-5-[2-(pivaloyloxy)ethyl]-1-(trimethylsilyl)oct-7-en-1-yn-4-ol

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

(3R,4S,5R)-4-[2-(pivaloyloxy)ethyl]oct-1-en-7-yne-3,5-diol

(3R,4S,5R)-4-[2-(pivaloyloxy)ethyl]oct-1-en-7-yne-3,5-diol

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

(3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(mesyloxy)-ethyl]oct-1-en-7-yne

上游原料

(3R,4R,5S)-3-benzoyloxy-5,6-epoxy-4-[(2-pivaloyloxy)ethyl]hex-1,5-diene (4R,5S,6R)-6-benzoyloxy-5-[2-(pivaloyloxy)ethyl]-1-(trimethylsilyl)oct-7-en-1-yn-4-ol (2S,3R,4R)-4-benzoyloxy-2-(tert-butyldimethylsilyl)oxy-3-(2-pivaloyloxyethyl)hex-5-en-1-ol 4,6-O-benzylidene-2-O-(tert-butyldimethylsilyl)-3-deoxy-3-C-(2-pivaloyloxyethyl)-α-D-altropyranoside (3R,4R,5S)-3-benzoyloxy-5-[(tert-butyldimethylsilyl)oxy]-4-[(2-pivaloyloxy)ethyl]-6-(tosyloxy)hex-1-ene 4,6-O-benzylidene-3-deoxy-2-O-(tert-butyldimethylsilyl)-3-C-ethenyl-α-D-altropyranoside methyl 4-O-benzoyl-6-bromo-2-O-(tert-butyldimethylsilyl)-3,6-dideoxy-3-C-(2-pivaloyloxyethyl)-α-D-altropyranoside (3R,4S,5R)-4-[2-(pivaloyloxy)ethyl]oct-1-en-7-yne-3,5-diol (3R,4S,5R)-3,5-bis(tert-butyldimethylsilyloxy)-4-[2-(pivaloyloxy)ethyl]oct-1-en-7-yne

下游产品

1α,25-dihydroxy-2α-[2-(imidazole-1-yl)ethyl]vitamin D3 1-(2-((1S,2S,6R,Z)-2,6-bis((tert-butyldimethylsilyl)oxy)-4-(2-((1R,3aS,7aR,E)-7a-methyl-1-((R)-6-methyl-6-((triethylsilyl)oxy)heptan-2-yl)octahydro-4H-inden-4-ylidene)ethylidene)-3-methylenecyclohexyl)ethyl)-1H-imidazole