百科

5-((1R,2S)-2-((S)-3-(4-fluorophenyl)-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)-1,2-bis((4-methoxybenzyl)oxy)ethyl)-N,N-dimethylpyrimidin-2-amine

CAS号：1442680-64-9

英文名：5-((1R,2S)-2-((S)-3-(4-fluorophenyl)-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)-1,2-bis((4-methoxybenzyl)oxy)ethyl)-N,N-dimethylpyrimidin-2-amine

分子式：C35H37FN6O5

分子量：640.704

合成路线

1442679-91-5

(2R,3S,4R)-4-(2-(dimethylamino)pyrimidin-5-yl)-3,4-bis((4-methoxybenzyl)oxy)-1-(trityloxy)butan-2-ol

1442680-64-9

5-((1R,2S)-2-((S)-3-(4-fluorophenyl)-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)-1,2-bis((4-methoxybenzyl)oxy)ethyl)-N,N-dimethylpyrimidin-2-amine

1442681-53-9

3,4-di-O-(p-methoxybenzyl)-6-O-trityl-D-galactal

1442680-64-9

5-((1R,2S)-2-((S)-3-(4-fluorophenyl)-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)-1,2-bis((4-methoxybenzyl)oxy)ethyl)-N,N-dimethylpyrimidin-2-amine

1442679-74-4

2-C-formyl-3,4-di-O-(p-methoxybenzyl)-6-O-trityl-D-galactal

1442680-64-9

5-((1R,2S)-2-((S)-3-(4-fluorophenyl)-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)-1,2-bis((4-methoxybenzyl)oxy)ethyl)-N,N-dimethylpyrimidin-2-amine

40274-29-1

1-(3-bromoprop-1-ynyl)-4-fluorobenzene

1442680-64-9

5-((1R,2S)-2-((S)-3-(4-fluorophenyl)-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)-1,2-bis((4-methoxybenzyl)oxy)ethyl)-N,N-dimethylpyrimidin-2-amine

136522-86-6

(2R,3R,4R)-2-((trityloxy)methyl)-3,4-dihydro-2H-pyran-3,4-diol

1442680-64-9

5-((1R,2S)-2-((S)-3-(4-fluorophenyl)-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)-1,2-bis((4-methoxybenzyl)oxy)ethyl)-N,N-dimethylpyrimidin-2-amine

上游原料

2-C-formyl-3,4-di-O-(p-methoxybenzyl)-6-O-trityl-D-galactal 3,4-di-O-(p-methoxybenzyl)-6-O-trityl-D-galactal (2R,3S,4R)-4-(2-(dimethylamino)pyrimidin-5-yl)-3,4-bis((4-methoxybenzyl)oxy)-1-(trityloxy)butan-2-ol 1-(3-bromoprop-1-ynyl)-4-fluorobenzene

下游产品

(1R,2S)-1-(2-(dimethylamino)pyrimidin-5-yl)-2-((S)-3-(4-fluorophenyl)-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)ethane-1,2-diol