百科

(4R,5R)-4-(2-(dimethylamino)pyrimidin-5-yl)-5-((S)-3-methyl-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)-1,3-dioxolan-2-one

(4R,5R)-4-(2-(dimethylamino)pyrimidin-5-yl)-5-((S)-3-methyl-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)-1,3-dioxolan-2-one

CAS号：1442681-47-1

英文名：(4R,5R)-4-(2-(dimethylamino)pyrimidin-5-yl)-5-((S)-3-methyl-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)-1,3-dioxolan-2-one

分子式：C15H18N6O4

分子量：346.341

合成路线

5-((1R,2R)-1,2-bis((4-methoxybenzyl)oxy)-2-((S)-3-methyl-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)ethyl)-N,N-dimethylpyrimidin-2-amine

5-((1R,2R)-1,2-bis((4-methoxybenzyl)oxy)-2-((S)-3-methyl-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)ethyl)-N,N-dimethylpyrimidin-2-amine

(4R,5R)-4-(2-(dimethylamino)pyrimidin-5-yl)-5-((S)-3-methyl-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)-1,3-dioxolan-2-one

(4R,5R)-4-(2-(dimethylamino)pyrimidin-5-yl)-5-((S)-3-methyl-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)-1,3-dioxolan-2-one

2-C-formyl-3,4-di-O-(p-methoxybenzyl)-6-O-trityl-D-glucal

2-C-formyl-3,4-di-O-(p-methoxybenzyl)-6-O-trityl-D-glucal

(4R,5R)-4-(2-(dimethylamino)pyrimidin-5-yl)-5-((S)-3-methyl-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)-1,3-dioxolan-2-one

(4R,5R)-4-(2-(dimethylamino)pyrimidin-5-yl)-5-((S)-3-methyl-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)-1,3-dioxolan-2-one

(2R,3R,4R)-4-(2-(dimethylamino)pyrimidin-5-yl)-3,4-bis((4-methoxybenzyl)oxy)-1-(trityloxy)butan-2-ol

(2R,3R,4R)-4-(2-(dimethylamino)pyrimidin-5-yl)-3,4-bis((4-methoxybenzyl)oxy)-1-(trityloxy)butan-2-ol

(4R,5R)-4-(2-(dimethylamino)pyrimidin-5-yl)-5-((S)-3-methyl-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)-1,3-dioxolan-2-one

(4R,5R)-4-(2-(dimethylamino)pyrimidin-5-yl)-5-((S)-3-methyl-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)-1,3-dioxolan-2-one

3,4-di-O-(p-methoxybenzyl)-6-O-trityl-D-glucal

3,4-di-O-(p-methoxybenzyl)-6-O-trityl-D-glucal

(4R,5R)-4-(2-(dimethylamino)pyrimidin-5-yl)-5-((S)-3-methyl-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)-1,3-dioxolan-2-one

(4R,5R)-4-(2-(dimethylamino)pyrimidin-5-yl)-5-((S)-3-methyl-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)-1,3-dioxolan-2-one

上游原料

2-C-formyl-3,4-di-O-(p-methoxybenzyl)-6-O-trityl-D-glucal 5-((1R,2R)-1,2-bis((4-methoxybenzyl)oxy)-2-((S)-3-methyl-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)ethyl)-N,N-dimethylpyrimidin-2-amine (2R,3R,4R)-4-(2-(dimethylamino)pyrimidin-5-yl)-3,4-bis((4-methoxybenzyl)oxy)-1-(trityloxy)butan-2-ol 3,4-di-O-(p-methoxybenzyl)-6-O-trityl-D-glucal

下游产品

(1R,2S)-2-azido-2-(2-(dimethylamino)pyrimidin-5-yl)-1-((S)-3-methyl-6,7-dihydro-4H-[1,2,3]triazolo[5,1-c][1,4]oxazin-7-yl)ethan-1-ol