百科

(2R,3S,4R,5R,6S,8R)-1-((R)-4-benzyl-2-thioxothiazolidin-3-yl)-3-((tert-butyldimethylsilyl)oxy)-9-((tert-butyldiphenylsilyl)oxy)-5-((4-methoxybenzyl)oxy)-2,4,6,8-tetramethylnonan-1-one

(2R,3S,4R,5R,6S,8R)-1-((R)-4-benzyl-2-thioxothiazolidin-3-yl)-3-((tert-butyldimethylsilyl)oxy)-9-((tert-butyldiphenylsilyl)oxy)-5-((4-methoxybenzyl)oxy)-2,4,6,8-tetramethylnonan-1-one

CAS号：1443051-58-8

英文名：(2R,3S,4R,5R,6S,8R)-1-((R)-4-benzyl-2-thioxothiazolidin-3-yl)-3-((tert-butyldimethylsilyl)oxy)-9-((tert-butyldiphenylsilyl)oxy)-5-((4-methoxybenzyl)oxy)-2,4,6,8-tetramethylnonan-1-one

分子式：C53H75NO5S2Si2

分子量：926.467

合成路线

(2S,3R,4S,6R)-7-((tert-butyldiphenylsilyl)oxy)-3-((4-methoxybenzyl)oxy)-2,4,6-trimethylheptan-1-ol

(2S,3R,4S,6R)-7-((tert-butyldiphenylsilyl)oxy)-3-((4-methoxybenzyl)oxy)-2,4,6-trimethylheptan-1-ol

(2R,3S,4R,5R,6S,8R)-1-((R)-4-benzyl-2-thioxothiazolidin-3-yl)-3-((tert-butyldimethylsilyl)oxy)-9-((tert-butyldiphenylsilyl)oxy)-5-((4-methoxybenzyl)oxy)-2,4,6,8-tetramethylnonan-1-one

(2R,3S,4R,5R,6S,8R)-1-((R)-4-benzyl-2-thioxothiazolidin-3-yl)-3-((tert-butyldimethylsilyl)oxy)-9-((tert-butyldiphenylsilyl)oxy)-5-((4-methoxybenzyl)oxy)-2,4,6,8-tetramethylnonan-1-one

(2R,4S)-4-((4R,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)-2-methylpentan-1-ol

(2R,4S)-4-((4R,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)-2-methylpentan-1-ol

(2R,3S,4R,5R,6S,8R)-1-((R)-4-benzyl-2-thioxothiazolidin-3-yl)-3-((tert-butyldimethylsilyl)oxy)-9-((tert-butyldiphenylsilyl)oxy)-5-((4-methoxybenzyl)oxy)-2,4,6,8-tetramethylnonan-1-one

(2R,3S,4R,5R,6S,8R)-1-((R)-4-benzyl-2-thioxothiazolidin-3-yl)-3-((tert-butyldimethylsilyl)oxy)-9-((tert-butyldiphenylsilyl)oxy)-5-((4-methoxybenzyl)oxy)-2,4,6,8-tetramethylnonan-1-one

tert-butyl(((2R,4S)-4-((4R,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)-2-methylpentyl)oxy)diphenylsilane

tert-butyl(((2R,4S)-4-((4R,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)-2-methylpentyl)oxy)diphenylsilane

(2R,3S,4R,5R,6S,8R)-1-((R)-4-benzyl-2-thioxothiazolidin-3-yl)-3-((tert-butyldimethylsilyl)oxy)-9-((tert-butyldiphenylsilyl)oxy)-5-((4-methoxybenzyl)oxy)-2,4,6,8-tetramethylnonan-1-one

(2R,3S,4R,5R,6S,8R)-1-((R)-4-benzyl-2-thioxothiazolidin-3-yl)-3-((tert-butyldimethylsilyl)oxy)-9-((tert-butyldiphenylsilyl)oxy)-5-((4-methoxybenzyl)oxy)-2,4,6,8-tetramethylnonan-1-one

上游原料

(2S,3R,4S,6R)-7-((tert-butyldiphenylsilyl)oxy)-3-((4-methoxybenzyl)oxy)-2,4,6-trimethylheptan-1-ol (2R,4S)-4-((4R,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)-2-methylpentan-1-ol tert-butyl(((2R,4S)-4-((4R,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)-2-methylpentyl)oxy)diphenylsilane

下游产品

(3R,4R,E)-6-iodo-4-methylhex-5-en-3-yl (2R,3S,4R,5R,6S,8R)-3-((tert-butyldimethylsilyl)oxy)-9-((tert-butyldiphenylsilyl)oxy)-5-((4-methoxybenzyl)oxy)-2,4,6,8-tetramethylnonanoate (2R,3S,4R,5R,6S,8R)-3-((tert-butyldimethylsilyl)oxy)-9-((tert-butyldiphenylsilyl)oxy)-5-((4-methoxybenzyl)oxy)-2,4,6,8-tetramethylnonanoic acid (2S,3R,4R,5R,6S,8R)-3-((tert-butyldimethylsilyl)oxy)-9-((tert-butyldiphenylsilyl)oxy)-5-((4-methoxybenzyl)oxy)-2,4,6,8-tetramethylnonan-1-ol (3R,4R,5E)-6-iodo-4-methylhex-5-en-3-yl (2R,3S,4S,5R,6S,8R)-3,9-dihydroxy-5-(4-methoxybenzyloxy)-2,4,6,8-tetramethylnonanoate