百科

(3S,9S,14aR)-3-((R)-7-((tert-butyldimethylsilyl)oxy)-6-oxooctyl)-9-(cyclohexylmethyl)-6,6-dimethyldecahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10-tetraone

(3S,9S,14aR)-3-((R)-7-((tert-butyldimethylsilyl)oxy)-6-oxooctyl)-9-(cyclohexylmethyl)-6,6-dimethyldecahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10-tetraone

CAS号：1445578-68-6

英文名：(3S,9S,14aR)-3-((R)-7-((tert-butyldimethylsilyl)oxy)-6-oxooctyl)-9-(cyclohexylmethyl)-6,6-dimethyldecahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10-tetraone

分子式：C34H60N4O6Si

分子量：648.949

上游原料

methyl 2-[(tert-butoxycarbonyl)amino]hex-5-enoate

methyl 2-[(tert-butoxycarbonyl)amino]hex-5-enoate

Z-Cha-D-Pro-O-t-Bu

Z-Cha-D-Pro-O-t-Bu

(-)-(R)-S-3-(tert-butyldimethylsilyloxy)-2-oxobutyl O-ethyl carbonodithioate

(-)-(R)-S-3-(tert-butyldimethylsilyloxy)-2-oxobutyl O-ethyl carbonodithioate

S-((7R)-7-((tert-butyldimethylsilyl)oxy)-1-((3S,9S,14aR)-9-(cyclohexylmethyl)-6,6-dimethyl-1,4,7,10-tetraoxotetradecahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecin-3-yl)-6-oxooctan-3-yl) O-ethyl carbonodithioate

S-((7R)-7-((tert-butyldimethylsilyl)oxy)-1-((3S,9S,14aR)-9-(cyclohexylmethyl)-6,6-dimethyl-1,4,7,10-tetraoxotetradecahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecin-3-yl)-6-oxooctan-3-yl) O-ethyl carbonodithioate

上游原料

methyl 2-[(tert-butoxycarbonyl)amino]hex-5-enoate Z-Cha-D-Pro-O-t-Bu (-)-(R)-S-3-(tert-butyldimethylsilyloxy)-2-oxobutyl O-ethyl carbonodithioate S-((7R)-7-((tert-butyldimethylsilyl)oxy)-1-((3S,9S,14aR)-9-(cyclohexylmethyl)-6,6-dimethyl-1,4,7,10-tetraoxotetradecahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecin-3-yl)-6-oxooctan-3-yl) O-ethyl carbonodithioate