百科

tert-butyl (S)-2-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-L-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-4-oxo-1,4-dihydroquinolin-7-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate

CAS号：1446139-13-4

英文名：tert-butyl (S)-2-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-L-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-4-oxo-1,4-dihydroquinolin-7-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate

分子式：C47H50F2N6O6

分子量：832.933

合成路线

1446138-84-6

(S)-tert-butyl 2-(5-(9,9-difluoro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate

1357259-72-3

methyl ((S)-1-((1R,3S,4S)-3-(7-bromo-4-oxo-1,4-dihydroquinolin-2-yl)-2-azabicyclo[2.2.1]heptan-2-yl)-3-methyl-1-oxobutan-2-yl)carbamate

1446139-13-4

tert-butyl (S)-2-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-L-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-4-oxo-1,4-dihydroquinolin-7-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate

1357259-69-8

tert-butyl (1R,3S,4S)-3-((2-acetyl-5-bromophenyl)carbamoyl)-2-azabicyclo[2.2.1]heptane-2-carboxylate

1446139-13-4

1357259-70-1

1446139-13-4

1446138-83-5

2-bromo-1-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)ethan-1-one

1446139-13-4

上游原料

2-bromo-1-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)ethan-1-one methyl ((S)-1-((1R,3S,4S)-3-(7-bromo-4-oxo-1,4-dihydroquinolin-2-yl)-2-azabicyclo[2.2.1]heptan-2-yl)-3-methyl-1-oxobutan-2-yl)carbamate (S)-tert-butyl 2-(5-(9,9-difluoro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate tert-butyl (1R,3S,4S)-3-((2-acetyl-5-bromophenyl)carbamoyl)-2-azabicyclo[2.2.1]heptane-2-carboxylate

下游产品

methyl ((S)-1-((S)-2-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-L-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-4-oxo-1,4-dihydroquinolin-7-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate