百科

tert-butyl (S)-2-(7-(4'-(2-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-1H-imidazol-5-yl)-[1,1'-biphenyl]-4-yl)-4-oxo-1,4-dihydroquinazolin-2-yl)pyrrolidine-1-carboxylate

tert-butyl (S)-2-(7-(4'-(2-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-1H-imidazol-5-yl)-[1,1'-biphenyl]-4-yl)-4-oxo-1,4-dihydroquinazolin-2-yl)pyrrolidine-1-carboxylate

CAS号：1446139-17-8

英文名：tert-butyl (S)-2-(7-(4'-(2-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-1H-imidazol-5-yl)-[1,1'-biphenyl]-4-yl)-4-oxo-1,4-dihydroquinazolin-2-yl)pyrrolidine-1-carboxylate

分子式：C41H46N6O5

分子量：702.841

合成路线

benzyl (S)-2-((5-bromo-2-carbamoylphenyl)carbamoyl)pyrrolidine-1-carboxylate

benzyl (S)-2-((5-bromo-2-carbamoylphenyl)carbamoyl)pyrrolidine-1-carboxylate

tert-butyl (S)-2-(7-(4'-(2-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-1H-imidazol-5-yl)-[1,1'-biphenyl]-4-yl)-4-oxo-1,4-dihydroquinazolin-2-yl)pyrrolidine-1-carboxylate

tert-butyl (S)-2-(7-(4'-(2-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-1H-imidazol-5-yl)-[1,1'-biphenyl]-4-yl)-4-oxo-1,4-dihydroquinazolin-2-yl)pyrrolidine-1-carboxylate

benzyl (S)-2-(7-bromo-4-oxo-3,4-dihydroquinazolin-2-yl)pyrrolidine-1-carboxylate

benzyl (S)-2-(7-bromo-4-oxo-3,4-dihydroquinazolin-2-yl)pyrrolidine-1-carboxylate

tert-butyl (S)-2-(7-(4'-(2-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-1H-imidazol-5-yl)-[1,1'-biphenyl]-4-yl)-4-oxo-1,4-dihydroquinazolin-2-yl)pyrrolidine-1-carboxylate

tert-butyl (S)-2-(7-(4'-(2-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-1H-imidazol-5-yl)-[1,1'-biphenyl]-4-yl)-4-oxo-1,4-dihydroquinazolin-2-yl)pyrrolidine-1-carboxylate

benzyl (S)-2-(chlorocarbonyl)pyrrolidine-1-carboxylate

benzyl (S)-2-(chlorocarbonyl)pyrrolidine-1-carboxylate

tert-butyl (S)-2-(7-(4'-(2-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-1H-imidazol-5-yl)-[1,1'-biphenyl]-4-yl)-4-oxo-1,4-dihydroquinazolin-2-yl)pyrrolidine-1-carboxylate

tert-butyl (S)-2-(7-(4'-(2-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-1H-imidazol-5-yl)-[1,1'-biphenyl]-4-yl)-4-oxo-1,4-dihydroquinazolin-2-yl)pyrrolidine-1-carboxylate

上游原料

benzyl (S)-2-(7-bromo-4-oxo-3,4-dihydroquinazolin-2-yl)pyrrolidine-1-carboxylate benzyl (S)-2-((5-bromo-2-carbamoylphenyl)carbamoyl)pyrrolidine-1-carboxylate

下游产品

methyl ((S)-1-((S)-2-(7-(4'-(2-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidin-2-yl)-1H-imidazol-5-yl)-[1,1'-biphenyl]-4-yl)-4-oxo-1,4-dihydroquinazolin-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate