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ethyl 8-chloro-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylate

ethyl 8-chloro-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylate

CAS号：1449278-52-7

英文名：ethyl 8-chloro-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylate

分子式

C17H12ClFN2O2

熔点

密度

分子量

330.741

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

ethyl 8-chloro-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylate

英文名称

ethyl 8-chloro-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylate

中文别名

英文别名

CAS号

1449278-52-7

分子式

C17H12ClFN2O2

分子量

330.741

精确质量

330.057

PSA

52.08

LOGP

4.266

合成路线

共找到43条合成路线 >

ethyl 2-(3-fluorophenyl)-8-oxo-7H-1,7-naphthyridine-5-carboxylate

ethyl 2-(3-fluorophenyl)-8-oxo-7H-1,7-naphthyridine-5-carboxylate

ethyl 8-chloro-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylate

ethyl 8-chloro-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylate

上游原料

共找到6个上游原料 >

5-bromo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridin-8-one

5-bromo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridin-8-one

ethyl 2-(3-fluorophenyl)-8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridine-5-carboxylate

ethyl 2-(3-fluorophenyl)-8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridine-5-carboxylate

ethyl 2-(3-fluorophenyl)-8-oxo-7H-1,7-naphthyridine-5-carboxylate

ethyl 2-(3-fluorophenyl)-8-oxo-7H-1,7-naphthyridine-5-carboxylate

ethyl 8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridine-5-carboxylate

ethyl 8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridine-5-carboxylate

ethyl 1-oxido-8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridin-1-ium-5-carboxylate

ethyl 1-oxido-8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridin-1-ium-5-carboxylate

ethyl 2-chloro-8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridine-5-carboxylate

ethyl 2-chloro-8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridine-5-carboxylate

下游产品

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ethyl 8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylate

ethyl 8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylate

8-amino-N-(azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide trifluoroacetate

8-amino-N-(azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide trifluoroacetate

8-amino-N-(azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide

8-amino-N-(azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide

8-amino-N-(1-(1,1-dioxidothiomorpholine-4-carbonyl)azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide

8-amino-N-(1-(1,1-dioxidothiomorpholine-4-carbonyl)azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide

tert-butyl 3-[[8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl]amino]azetidine-1-carboxylate

tert-butyl 3-[[8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl]amino]azetidine-1-carboxylate

N-(1-(8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl)azetidin-3-yl)cyclopropanecarboxamide

N-(1-(8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl)azetidin-3-yl)cyclopropanecarboxamide

上游原料

5-bromo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridin-8-one ethyl 2-(3-fluorophenyl)-8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridine-5-carboxylate ethyl 2-(3-fluorophenyl)-8-oxo-7H-1,7-naphthyridine-5-carboxylate ethyl 8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridine-5-carboxylate ethyl 1-oxido-8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridin-1-ium-5-carboxylate ethyl 2-chloro-8-oxo-7-(2-trimethylsilylethoxymethyl)-1,7-naphthyridine-5-carboxylate

下游产品

ethyl 8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylate 8-amino-N-(azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide trifluoroacetate 8-amino-N-(azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide 8-amino-N-(1-(1,1-dioxidothiomorpholine-4-carbonyl)azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide tert-butyl 3-[[8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl]amino]azetidine-1-carboxylate N-(1-(8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl)azetidin-3-yl)cyclopropanecarboxamide 8-amino-2-(3-fluorophenyl)-N-(1-propionylazetidin-3-yl)-1,7-naphthyridine-5-carboxamide N-(1-(8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl)azetidin-3-yl)-N-(cyclopropanecarbonyl)cyclopropanecarboxamide N-(1-(8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl)azetidin-3-yl)acetamide 8-amino-N-cyclopropyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide 8-amino-N-cyclobutyl-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide 2-(3-fluorophenyl)-5-iodo-1,7-naphthyridin-8-amine 8-amino-2-(3-fluorophenyl)-N-(1-(morpholine-4-carbonyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide 2-(3-fluorophenyl)-5-(1,3,4-oxadiazol-2-yl)-1,7-naphthyridin-8-amine 8-amino-N-(azetidin-3-yl)-2-(3-fluorophenyl)-N-methyl-1,7-naphthyridine-5-carboxamide N-(1-(8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl)azetidin-3-yl)propionamide 8-amino-2-(3-fluorophenyl)-N-(1-(methylcarbamoyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide 2-(3-fluorophenyl)-1,7-naphthyridin-8-amine 8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxylic acid 8-amino-2-(3-fluorophenyl)-N-(1-(methylsulfonyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide 8-amino-2-(3-fluorophenyl)-N-(1-((trifluoromethyl)sulfonyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide (R)-8-amino-2-(3-fluorophenyl)-N-(1-(2-hydroxypropanoyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide (S)-8-amino-2-(3-fluorophenyl)-N-(1-(2-hydroxypropanoyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide 8-amino-N-(1-(cyclopropanecarbonyl)azetidin-3-yl)-2-(3-fluorophenyl)-N-methyl-1,7-naphthyridin-5-carboxamide 8-amino-N-(1-(N,N-dimethylsulfamoyl)azetidin-3-yl)-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide 2-(3-fluorophenyl)-5-(1H-1,2,4-triazol-5-yl)-1,7-naphthyridin-8-amine 8-amino-2-(3-fluorophenyl)-N-(1-(2-morpholinoacetyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide 8-amino-2-(3-fluorophenyl)-N-(1-(2-hydroxypropanoyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide 8-amino-2-(3-fluorophenyl)-N-(1-sulfamoylazetidin-3-yl)-1,7-naphthyridine-5-carboxamide 8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide 8-amino-2-(3-fluorophenyl)-N-(1-(oxetane-3-carbonyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide 8-amino-2-(3-fluorophenyl)-N-(1-(2,2,2-trifluoroethyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide GNE-495 8-amino-2-(3-fluorophenyl)-N-(oxetan-3-yl)-1,7-naphthyridine-5-carboxamide 2-(3-fluorophenyl)-5-(1-(2-morpholinoethyl)-1H-imidazol-4-yl)-1,7-naphthyridin-8-amine 8-amino-2-(3-fluorophenyl)-N-(1-(2-methoxyacetyl)azetidin-3-yl)-1,7-naphthyridine-5-carboxamide 8-amino-2-(3-fluorophenyl)-N-isobutyl-1,7-naphthyridine-5-carboxamide 8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbohydrazide tert-butyl (1-(8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl)azetidin-3-yl)carbamate (8-amino-2-(3-fluorophenyl)-1,7-naphthyridin-5-yl)(3-aminoazetidin-1-yl)methanone tert-butyl 3-[[8-amino-2-(3-fluorophenyl)-1,7-naphthyridine-5-carbonyl]amino]azetidine-1-carboxylate