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2-((2R,6S,8R,10R)-10-(((3R,4S)-4-(benzyloxy)-3-((triethylsilyl)oxy)pentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

CAS号：1449419-31-1

英文名：2-((2R,6S,8R,10R)-10-(((3R,4S)-4-(benzyloxy)-3-((triethylsilyl)oxy)pentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

分子式：C48H68O9Si

分子量：817.134

合成路线

1449419-37-7

(2R,4R,6R,8R)-8-allyl-2-(4-(3-(benzyloxy)phenyl)butyl)-11,11-dimethyl-1,7-dioxaspiro[5.5]undecan-4-yl (3R,4S)-4-(benzyloxy)-3-((triethylsilyl)oxy)pentanoate

1449419-31-1

2-((2R,6S,8R,10R)-10-(((3R,4S)-4-(benzyloxy)-3-((triethylsilyl)oxy)pentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

1449419-34-4

(2R,4R,6R,8R)-8-allyl-2-(4-(3-(benzyloxy)phenyl)butyl)-11,11-dimethyl-1,7-dioxaspiro[5.5]undecan-4-yl (3R,4S)-4-(benzyloxy)-3-hydroxypentanoate

1449419-31-1

2-((2R,6S,8R,10R)-10-(((3R,4S)-4-(benzyloxy)-3-((triethylsilyl)oxy)pentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

1449419-19-5

(2R,3R)-4-(1,3-dithian-2-yl)-3-((4-methoxybenzyl)oxy)butan-2-ol

1449419-31-1

2-((2R,6S,8R,10R)-10-(((3R,4S)-4-(benzyloxy)-3-((triethylsilyl)oxy)pentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

1449419-20-8

(2S,3R)-4-(1,3-dithian-2-yl)-3-((4-methoxybenzyl)oxy)butan-2-ol

1449419-31-1

2-((2R,6S,8R,10R)-10-(((3R,4S)-4-(benzyloxy)-3-((triethylsilyl)oxy)pentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

1449419-22-0

2-((2R,3S)-3-(benzyloxy)-2-((4-methoxybenzyl)oxy)butyl)-1,3-dithiane

1449419-31-1

2-((2R,6S,8R,10R)-10-(((3R,4S)-4-(benzyloxy)-3-((triethylsilyl)oxy)pentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

1449419-23-1

(3R,4S)-4-(benzyloxy)-3-((4-methoxybenzyl)oxy)pentanal

1449419-31-1

2-((2R,6S,8R,10R)-10-(((3R,4S)-4-(benzyloxy)-3-((triethylsilyl)oxy)pentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

1449419-25-3

(3R,4S)-4-(benzyloxy)-3-((4-methoxybenzyl)oxy)pentanoic acid

1449419-31-1

2-((2R,6S,8R,10R)-10-(((3R,4S)-4-(benzyloxy)-3-((triethylsilyl)oxy)pentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

1449419-28-6

(2R,4R,6R,8R)-8-allyl-2-(4-(3-(benzyloxy)phenyl)butyl)-11,11-dimethyl-1,7-dioxaspiro[5.5]undecan-4-yl (3R,4S)-4-(benzyloxy)-3-((4-methoxybenzyl)oxy)pentanoate

1449419-31-1

2-((2R,6S,8R,10R)-10-(((3R,4S)-4-(benzyloxy)-3-((triethylsilyl)oxy)pentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

上游原料

(2R,4R,6R,8R)-8-allyl-2-(4-(3-(benzyloxy)phenyl)butyl)-11,11-dimethyl-1,7-dioxaspiro[5.5]undecan-4-yl (3R,4S)-4-(benzyloxy)-3-hydroxypentanoate (2S,3R)-4-(1,3-dithian-2-yl)-3-((4-methoxybenzyl)oxy)butan-2-ol (3R,4S)-4-(benzyloxy)-3-((4-methoxybenzyl)oxy)pentanoic acid (2R,4R,6R,8R)-8-allyl-2-(4-(3-(benzyloxy)phenyl)butyl)-11,11-dimethyl-1,7-dioxaspiro[5.5]undecan-4-yl (3R,4S)-4-(benzyloxy)-3-((triethylsilyl)oxy)pentanoate (2R,3R)-4-(1,3-dithian-2-yl)-3-((4-methoxybenzyl)oxy)butan-2-ol (2R,4R,6R,8R)-8-allyl-2-(4-(3-(benzyloxy)phenyl)butyl)-11,11-dimethyl-1,7-dioxaspiro[5.5]undecan-4-yl (3R,4S)-4-(benzyloxy)-3-((4-methoxybenzyl)oxy)pentanoate 2-((2R,3S)-3-(benzyloxy)-2-((4-methoxybenzyl)oxy)butyl)-1,3-dithiane (3R,4S)-4-(benzyloxy)-3-((4-methoxybenzyl)oxy)pentanal

下游产品

(1S,3R,5R,9R,13R)-9-((S)-1-hydroxyethyl)-3-(4-(3-hydroxyphenyl)butyl)-16,16-dimethyl-2,6,10,17-tetraoxatricyclo[11.3.1.11,5]octadecane-7,11-dione (1S,3R,5R,9R,13R)-9-((S)-1-(benzyloxy)ethyl)-3-(4-(3-(benzyloxy)phenyl)butyl)-16,16-dimethyl-2,6,10,17-tetraoxatricyclo[11.3.1.11,5]octadecane-7,11-dione 2-((2R,6S,8R,10R)-10-(((3R,4S)-4-(benzyloxy)-3-hydroxypentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid