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2-((2R,6S,8R,10R)-10-(((3R,4R)-4-(benzyloxy)-3-hydroxypentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

CAS号：1449419-39-9

英文名：2-((2R,6S,8R,10R)-10-(((3R,4R)-4-(benzyloxy)-3-hydroxypentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

分子式：C42H54O9

分子量：702.873

合成路线

1449419-30-0

2-((2R,6S,8R,10R)-10-(((3R,4R)-4-(benzyloxy)-3-((triethylsilyl)oxy)pentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

1449419-39-9

2-((2R,6S,8R,10R)-10-(((3R,4R)-4-(benzyloxy)-3-hydroxypentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

1449419-19-5

(2R,3R)-4-(1,3-dithian-2-yl)-3-((4-methoxybenzyl)oxy)butan-2-ol

1449419-39-9

2-((2R,6S,8R,10R)-10-(((3R,4R)-4-(benzyloxy)-3-hydroxypentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

1449419-21-9

2-((2R,3R)-3-(benzyloxy)-2-((4-methoxybenzyl)oxy)butyl)-1,3-dithiane

1449419-39-9

2-((2R,6S,8R,10R)-10-(((3R,4R)-4-(benzyloxy)-3-hydroxypentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

206255-41-6

(3R,4R)-4-Benzyloxy-3-(4-methoxy-benzyloxy)-pentanal

1449419-39-9

2-((2R,6S,8R,10R)-10-(((3R,4R)-4-(benzyloxy)-3-hydroxypentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

1449419-24-2

(3R,4R)-4-(benzyloxy)-3-((4-methoxybenzyl)oxy)pentanoic acid

1449419-39-9

2-((2R,6S,8R,10R)-10-(((3R,4R)-4-(benzyloxy)-3-hydroxypentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

1449419-27-5

(2R,4R,6R,8R)-8-allyl-2-(4-(3-(benzyloxy)phenyl)butyl)-11,11-dimethyl-1,7-dioxaspiro[5.5]undecan-4-yl (3R,4R)-4-(benzyloxy)-3-((4-methoxybenzyl)oxy)pentanoate

1449419-39-9

2-((2R,6S,8R,10R)-10-(((3R,4R)-4-(benzyloxy)-3-hydroxypentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

1449419-33-3

(2R,4R,6R,8R)-8-allyl-2-(4-(3-(benzyloxy)phenyl)butyl)-11,11-dimethyl-1,7-dioxaspiro[5.5]undecan-4-yl (3R,4R)-4-(benzyloxy)-3-hydroxypentanoate

1449419-39-9

2-((2R,6S,8R,10R)-10-(((3R,4R)-4-(benzyloxy)-3-hydroxypentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

1449419-36-6

(2R,4R,6R,8R)-8-allyl-2-(4-(3-(benzyloxy)phenyl)butyl)-11,11-dimethyl-1,7-dioxaspiro[5.5]undecan-4-yl (3R,4R)-4-(benzyloxy)-3-((triethylsilyl)oxy)pentanoate

1449419-39-9

2-((2R,6S,8R,10R)-10-(((3R,4R)-4-(benzyloxy)-3-hydroxypentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid

上游原料

(3R,4R)-4-(benzyloxy)-3-((4-methoxybenzyl)oxy)pentanoic acid 2-((2R,3R)-3-(benzyloxy)-2-((4-methoxybenzyl)oxy)butyl)-1,3-dithiane (2R,4R,6R,8R)-8-allyl-2-(4-(3-(benzyloxy)phenyl)butyl)-11,11-dimethyl-1,7-dioxaspiro[5.5]undecan-4-yl (3R,4R)-4-(benzyloxy)-3-((triethylsilyl)oxy)pentanoate (2R,4R,6R,8R)-8-allyl-2-(4-(3-(benzyloxy)phenyl)butyl)-11,11-dimethyl-1,7-dioxaspiro[5.5]undecan-4-yl (3R,4R)-4-(benzyloxy)-3-((4-methoxybenzyl)oxy)pentanoate 2-((2R,6S,8R,10R)-10-(((3R,4R)-4-(benzyloxy)-3-((triethylsilyl)oxy)pentanoyl)oxy)-8-(4-(3-(benzyloxy)phenyl)butyl)-5,5-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl)acetic acid (2R,3R)-4-(1,3-dithian-2-yl)-3-((4-methoxybenzyl)oxy)butan-2-ol (3R,4R)-4-Benzyloxy-3-(4-methoxy-benzyloxy)-pentanal (2R,4R,6R,8R)-8-allyl-2-(4-(3-(benzyloxy)phenyl)butyl)-11,11-dimethyl-1,7-dioxaspiro[5.5]undecan-4-yl (3R,4R)-4-(benzyloxy)-3-hydroxypentanoate

下游产品

(1S,3R,5R,9R,13R)-9-((R)-1-hydroxyethyl)-3-(4-(3-hydroxyphenyl)butyl)-16,16-dimethyl-2,6,10,17-tetraoxatricyclo[11.3.1.11,5]octadecane-7,11-dione (1S,3R,5R,9R,13R)-9-((R)-1-(benzyloxy)ethyl)-3-(4-(3-(benzyloxy)phenyl)butyl)-16,16-dimethyl-2,6,10,17-tetraoxatricyclo[11.3.1.11,5]octadecane-7,11-dione