百科

(3aS,5aS,5bR,8aR,9aR)-7,7-dimethyl-3a,4,5a,5b,8a,9a-hexahydro-3H-[1,3]dioxolo[4'',5'':4',5']furo[2',3':5,6]pyrano[4,3-c]isoxazole

(3aS,5aS,5bR,8aR,9aR)-7,7-dimethyl-3a,4,5a,5b,8a,9a-hexahydro-3H-[1,3]dioxolo[4'',5'':4',5']furo[2',3':5,6]pyrano[4,3-c]isoxazole

CAS号：1454318-30-9

英文名：(3aS,5aS,5bR,8aR,9aR)-7,7-dimethyl-3a,4,5a,5b,8a,9a-hexahydro-3H-[1,3]dioxolo[4'',5'':4',5']furo[2',3':5,6]pyrano[4,3-c]isoxazole

分子式：C11H15NO5

分子量：241.24

合成路线

3-O-allyl-1,2-O-isopropylidene-α-D-arabinopentodialdo-1,4-furanose oxime

3-O-allyl-1,2-O-isopropylidene-α-D-arabinopentodialdo-1,4-furanose oxime

(3aS,5aS,5bR,8aR,9aR)-7,7-dimethyl-3a,4,5a,5b,8a,9a-hexahydro-3H-[1,3]dioxolo[4'',5'':4',5']furo[2',3':5,6]pyrano[4,3-c]isoxazole

(3aS,5aS,5bR,8aR,9aR)-7,7-dimethyl-3a,4,5a,5b,8a,9a-hexahydro-3H-[1,3]dioxolo[4'',5'':4',5']furo[2',3':5,6]pyrano[4,3-c]isoxazole

3-O-Allyl-1,2-O-isopropylidene-α-D-xylo-pentodialdose

3-O-Allyl-1,2-O-isopropylidene-α-D-xylo-pentodialdose

(3aS,5aS,5bR,8aR,9aR)-7,7-dimethyl-3a,4,5a,5b,8a,9a-hexahydro-3H-[1,3]dioxolo[4'',5'':4',5']furo[2',3':5,6]pyrano[4,3-c]isoxazole

(3aS,5aS,5bR,8aR,9aR)-7,7-dimethyl-3a,4,5a,5b,8a,9a-hexahydro-3H-[1,3]dioxolo[4'',5'':4',5']furo[2',3':5,6]pyrano[4,3-c]isoxazole

(2S,3R,4R,5R)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-2,3,4-triol

(2S,3R,4R,5R)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-2,3,4-triol

(3aS,5aS,5bR,8aR,9aR)-7,7-dimethyl-3a,4,5a,5b,8a,9a-hexahydro-3H-[1,3]dioxolo[4'',5'':4',5']furo[2',3':5,6]pyrano[4,3-c]isoxazole

(3aS,5aS,5bR,8aR,9aR)-7,7-dimethyl-3a,4,5a,5b,8a,9a-hexahydro-3H-[1,3]dioxolo[4'',5'':4',5']furo[2',3':5,6]pyrano[4,3-c]isoxazole

3-O-allyl-1,2-O-isopropylidene-α-D-glucofuranose

3-O-allyl-1,2-O-isopropylidene-α-D-glucofuranose

(3aS,5aS,5bR,8aR,9aR)-7,7-dimethyl-3a,4,5a,5b,8a,9a-hexahydro-3H-[1,3]dioxolo[4'',5'':4',5']furo[2',3':5,6]pyrano[4,3-c]isoxazole

(3aS,5aS,5bR,8aR,9aR)-7,7-dimethyl-3a,4,5a,5b,8a,9a-hexahydro-3H-[1,3]dioxolo[4'',5'':4',5']furo[2',3':5,6]pyrano[4,3-c]isoxazole

上游原料

3-O-Allyl-1,2-O-isopropylidene-α-D-xylo-pentodialdose 3-O-allyl-1,2-O-isopropylidene-α-D-arabinopentodialdo-1,4-furanose oxime 3-O-allyl-1,2-O-isopropylidene-α-D-glucofuranose

下游产品

methyl (3aR,3bS,5aS,12aR,12bR,13aR)-2,2-dimethyl-11-oxo-3a,3b,5a,11,12,12a,12b,13a-octahydro-5H,6H-[1,3]dioxolo[4'',5'':4',5']furo[2',3':5,6]pyrano[4,3-e][1,2,3]triazolo[1,5-a][1,4]diazepine-10-carboxylate dimethyl 1-(((3aR,3bS,6S,7R,7aR,8aR)-7-((tert-butoxycarbonyl)amino)-2,2-dimethylhexahydro-5H-[1,3]dioxolo[4',5':4,5]furo[3,2-b]pyran-6-yl)methyl)-1H-1,2,3-triazole-4,5-dicarboxylate tert-butyl ((3aR,3bS,6S,7R,7aR,8aR)-6-(azidomethyl)-2,2-dimethylhexahydro-5H-[1,3]dioxolo[4',5':4,5]furo[3,2-b]pyran-7-yl)carbamate ((3aR,3bS,6S,7R,7aR,8aR)-7-((tert-butoxycarbonyl)amino)-2,2-dimethylhexahydro-5H-[1,3]dioxolo[4',5':4,5]furo[3,2-b]pyran-6-yl)methyl 4-methylbenzenesulfonate tert-butyl ((3aR,3bS,6R,7R,7aR,8aR)-6-(hydroxymethyl)-2,2-dimethylhexahydro-5H-[1,3]dioxolo[4',5':4,5]furo[3,2-b]pyran-7-yl)carbamate