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(2R,3R)-3-((4R,5R)-2,2-dimethyl-5-(3-methylbut-1-yn-1-yl)-1,3-dioxolan-4-yl)-3-hydroxy-2-methoxy-N-((S)-2-oxoazepan-3-yl)propanamide

(2R,3R)-3-((4R,5R)-2,2-dimethyl-5-(3-methylbut-1-yn-1-yl)-1,3-dioxolan-4-yl)-3-hydroxy-2-methoxy-N-((S)-2-oxoazepan-3-yl)propanamide

CAS号：1456796-00-1

英文名：(2R,3R)-3-((4R,5R)-2,2-dimethyl-5-(3-methylbut-1-yn-1-yl)-1,3-dioxolan-4-yl)-3-hydroxy-2-methoxy-N-((S)-2-oxoazepan-3-yl)propanamide

分子式：C20H32N2O6

分子量：396.478

合成路线

((2S,3R)-3-((4S,5R)-5-(2,2-dibromovinyl)-2,2-dimethyl-1,3-dioxolan-4-yl)oxiran-2-yl)((S)-2,2-dimethyl-4-(2-(methylthio)ethyl)oxazolidin-3-yl)methanone

((2S,3R)-3-((4S,5R)-5-(2,2-dibromovinyl)-2,2-dimethyl-1,3-dioxolan-4-yl)oxiran-2-yl)((S)-2,2-dimethyl-4-(2-(methylthio)ethyl)oxazolidin-3-yl)methanone

(2R,3R)-3-((4R,5R)-2,2-dimethyl-5-(3-methylbut-1-yn-1-yl)-1,3-dioxolan-4-yl)-3-hydroxy-2-methoxy-N-((S)-2-oxoazepan-3-yl)propanamide

(2R,3R)-3-((4R,5R)-2,2-dimethyl-5-(3-methylbut-1-yn-1-yl)-1,3-dioxolan-4-yl)-3-hydroxy-2-methoxy-N-((S)-2-oxoazepan-3-yl)propanamide

((2R,3S)-3-((4S,5R)-5-(2,2-dibromovinyl)-2,2-dimethyl-1,3-dioxolan-4-yl)oxiran-2-yl)methanol

((2R,3S)-3-((4S,5R)-5-(2,2-dibromovinyl)-2,2-dimethyl-1,3-dioxolan-4-yl)oxiran-2-yl)methanol

(2R,3R)-3-((4R,5R)-2,2-dimethyl-5-(3-methylbut-1-yn-1-yl)-1,3-dioxolan-4-yl)-3-hydroxy-2-methoxy-N-((S)-2-oxoazepan-3-yl)propanamide

(2R,3R)-3-((4R,5R)-2,2-dimethyl-5-(3-methylbut-1-yn-1-yl)-1,3-dioxolan-4-yl)-3-hydroxy-2-methoxy-N-((S)-2-oxoazepan-3-yl)propanamide

((4R,5R)-5-(2,2-dibromovinyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methanol

((4R,5R)-5-(2,2-dibromovinyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methanol

(2R,3R)-3-((4R,5R)-2,2-dimethyl-5-(3-methylbut-1-yn-1-yl)-1,3-dioxolan-4-yl)-3-hydroxy-2-methoxy-N-((S)-2-oxoazepan-3-yl)propanamide

(2R,3R)-3-((4R,5R)-2,2-dimethyl-5-(3-methylbut-1-yn-1-yl)-1,3-dioxolan-4-yl)-3-hydroxy-2-methoxy-N-((S)-2-oxoazepan-3-yl)propanamide

上游原料

((2S,3R)-3-((4S,5R)-5-(2,2-dibromovinyl)-2,2-dimethyl-1,3-dioxolan-4-yl)oxiran-2-yl)((S)-2,2-dimethyl-4-(2-(methylthio)ethyl)oxazolidin-3-yl)methanone ((4R,5R)-5-(2,2-dibromovinyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methanol ((2R,3S)-3-((4S,5R)-5-(2,2-dibromovinyl)-2,2-dimethyl-1,3-dioxolan-4-yl)oxiran-2-yl)methanol

下游产品

(2R,3R,4S,5R)-3,4,5-Trihydroxy-2-methoxy-8-methyl-non-6-ynoic acid ((S)-2-oxo-azepan-3-yl)-amide