化合物简介
Selegiline, also known as L-deprenyl is a substituted phenethylamine that at normal clinical doses it is a selective irreversible MAO-B inhibitor. In larger doses it loses its specificity and also inhibits MAO-A. It is available in pill form under many brand names and is used to reduce symptoms in early-stage Parkinson's disease. A transdermal patch (brand name, Emsam) is used to treat depression.
基本信息
中文名称
盐酸司来吉兰
英文名称
selegiline hydrochloride
中文别名
盐酸丙炔苯并胺、(R)-N,alpha-二甲基-N-(2-丙炔基)苯乙胺盐酸盐
英文别名
(R)-N-Methyl-N-(1-phenylpropan-2-yl)prop-2-yn-1-amine hydrochloride、Selegiline HCl、R-(−)-Deprenyl hydrochloride、(2R)-N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine,hydrochloride
CAS号
14611-52-0
分子式
C13H18ClN
分子量
223.742
精确质量
223.113
PSA
3.24
LOGP
2.9846
编号系统
MDL号
MFCD00069299
物化性质
外观与性状
白色结晶固体
密度
0.954g/cm3
沸点
272.5ºC at 760mmHg
熔点
141-142ºC
闪点
108.4ºC
安全信息
RTECS号
DA0292500
安全说明
S22-S26
WGK Germany
3
危险品运输编码
UN 3249
海关编码
2921519090
危险类别
6.1(b)
包装等级
III