百科

(1R,3R)-2,2,2-trichloroethyl 1-acetoxymethyl-3-<(2R,5S)-5-benzyloxymethyl-1-tert-butoxycarbonylpyrrolidin-2-yl>-8-methoxy-3,4-dihydro-2(1H)-isoquinolinecarboxylate

(1R,3R)-2,2,2-trichloroethyl 1-acetoxymethyl-3-<(2R,5S)-5-benzyloxymethyl-1-tert-butoxycarbonylpyrrolidin-2-yl>-8-methoxy-3,4-dihydro-2(1H)-isoquinolinecarboxylate

CAS号：154978-04-8

英文名：(1R,3R)-2,2,2-trichloroethyl 1-acetoxymethyl-3-<(2R,5S)-5-benzyloxymethyl-1-tert-butoxycarbonylpyrrolidin-2-yl>-8-methoxy-3,4-dihydro-2(1H)-isoquinolinecarboxylate

分子式：C33H41Cl3N2O8

分子量：700.046

合成路线

(1R,3S)-3-((2R,5S)-5-Benzyloxymethyl-1-tert-butoxycarbonyl-pyrrolidin-2-yl)-8-methoxy-1-((1R,2R)-1,2,3-trihydroxy-propyl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid 2,2,2-trichloro-ethyl ester

(1R,3S)-3-((2R,5S)-5-Benzyloxymethyl-1-tert-butoxycarbonyl-pyrrolidin-2-yl)-8-methoxy-1-((1R,2R)-1,2,3-trihydroxy-propyl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid 2,2,2-trichloro-ethyl ester

(1R,3R)-2,2,2-trichloroethyl 1-acetoxymethyl-3-<(2R,5S)-5-benzyloxymethyl-1-tert-butoxycarbonylpyrrolidin-2-yl>-8-methoxy-3,4-dihydro-2(1H)-isoquinolinecarboxylate

(1R,3R)-2,2,2-trichloroethyl 1-acetoxymethyl-3-<(2R,5S)-5-benzyloxymethyl-1-tert-butoxycarbonylpyrrolidin-2-yl>-8-methoxy-3,4-dihydro-2(1H)-isoquinolinecarboxylate

上游原料

(1R,3S)-3-((2R,5S)-5-Benzyloxymethyl-1-tert-butoxycarbonyl-pyrrolidin-2-yl)-8-methoxy-1-((1R,2R)-1,2,3-trihydroxy-propyl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid 2,2,2-trichloro-ethyl ester

下游产品

(5R,7R,8S,11R,11aS)-5-acetoxymethyl-7-cyano-4-methoxy-5,7,8,9,10,11,11a,12-octahydro-8,11-iminoazepino<1,2-b>isoquinoline (5R,7R,8S,11R,11aS)-5-acetoxymethyl-13-tert-butoxycarbonyl-7-hydroxy-4-methoxy-5,7,8,9,10,11,11a,12-octahydro-8,11-iminoazepino<1,2-b>isoquinoline